Význam vulnerabilních aterosklerotických plátů a možnosti jejich detekce pomocí intravaskulární spektroskopie
[Detection of vulnerable atherosclerotic plaque with near-infrared spectroscopy: a systematic review]

. 2014 Apr ; 60 (4) : 375-9.

Jazyk čeština Země Česko Médium print

Typ dokumentu časopisecké články, přehledy, systematický přehled

Perzistentní odkaz   https://www.medvik.cz/link/pmid24986001
Odkazy

PubMed 24986001
PII: 49031

The term vulnerable atherosclerotic plaque is used to describe an atherosclerotic lesion with a high probability of rupture and thrombosis causing an acute coronary event or stroke. Pathogenesis of the vulnerable plaque has been well described pathologically and on experimental models. Detection of vulnerable plaques in vivo has been limited so far. There has been lack of methods able to predict future event from certain lesion characteristics that were rigorously validated on prospective clinical trials. Intravascular near-infrared spectroscopy is a novel technique that has been intentionally developed for the identification of a lipid core within a plaque. Results from recent clinical trials seem promising. This review briefly summarizes current knowledge in the field of near-infrared spectroscopy.

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