We wish to offer some comments on the article by H. Liu et al. entitled "Evaluation of antioxidant and immunity activities of quercetin in isoproterenol-treated rats", published in Molecules in 2012 [1]. [...].

Charles University Prague Faculty of Medicine in Hradec Králové Šimkova 870 500 38 Hradec Králové Czech Republic

Department of Pharmacology and Toxicology Charles University Prague Faculty of Pharmacy in Hradec Králové Heyrovského 1203 500 05 Hradec Králové Czech Republic

Molecules. 2012 Apr 10;17(4):4281-91. doi: 10.3390/molecules17044281. PubMed

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Liu H., Zhang L., Lu S. Evaluation of antioxidant and immunity activities of quercetin in isoproterenol-treated rats. Molecules. 2012;17:4281–4291. doi: 10.3390/molecules17044281. PubMed DOI PMC

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Comprehensive review of cardiovascular toxicity of drugs and related agents

Intravenous rutin in rat exacerbates isoprenaline-induced cardiotoxicity likely due to intracellular oxidative stress