Metformin: the past, presence, and future
Language English Country Italy Media print-electronic
Document type Journal Article, Review
PubMed
25532538
PII: R10Y9999N00A140044
Knihovny.cz E-resources
- MeSH
- Administration, Oral MeSH
- Diabetes Mellitus, Type 2 drug therapy MeSH
- Weight Loss drug effects MeSH
- Risk Assessment MeSH
- Hypoglycemic Agents administration & dosage adverse effects therapeutic use MeSH
- Clinical Trials as Topic MeSH
- Humans MeSH
- Evidence-Based Medicine MeSH
- Metformin administration & dosage adverse effects therapeutic use MeSH
- Randomized Controlled Trials as Topic MeSH
- Risk Factors MeSH
- Treatment Outcome MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
- Names of Substances
- Hypoglycemic Agents MeSH
- Metformin MeSH
The authors trace the history of metformin and its clinical use to the present day. Recent insights into its mode of action and latest data from experimental and clinical medicine have unraveled novel properties of metformin, which may be particularly useful in the treatment of conditions other than diabetes. Results of ongoing clinical trials will show whether or not the hypoglycemic effect of metformin will become only one of the many to be employed in clinical practice.
