Occipitocervical stabilization using bilateral laminar C2 screws in children with mucopolysaccharidosis IVA
Jazyk angličtina Země Německo Médium print-electronic
Typ dokumentu hodnotící studie, časopisecké články, práce podpořená grantem
PubMed
25794700
DOI
10.1007/s00586-015-3879-0
PII: 10.1007/s00586-015-3879-0
Knihovny.cz E-zdroje
- Klíčová slova
- Laminar, Mucopolysaccharidosis, Screw, Stabilization,
- MeSH
- atlantookcipitální kloub chirurgie MeSH
- chirurgická dekomprese přístrojové vybavení metody MeSH
- dítě MeSH
- fúze páteře přístrojové vybavení metody MeSH
- komprese míchy diagnóza etiologie chirurgie MeSH
- kostní šrouby * MeSH
- krční obratle chirurgie MeSH
- lidé MeSH
- magnetická rezonanční tomografie metody MeSH
- mladiství MeSH
- mukopolysacharidóza IV komplikace MeSH
- nestabilita kloubu chirurgie MeSH
- počítačová rentgenová tomografie metody MeSH
- studie proveditelnosti MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- hodnotící studie MeSH
- práce podpořená grantem MeSH
PURPOSE: Mucopolysaccharidosis IVA (MPS IVA) is a multisystemic storage disorder. Patient's disability and life expectancy depends upon skeletal complications, including cervical myelopathy due to upper cervical compression or instability. Posterior decompression followed by occipitocervical fixation or C1-2 fusion are the most frequently recommended surgical interventions. The bony elements of C1 and C2 are often inadequately developed making routine screw insertion difficult. The main purpose of this work was to present novel technique of occipitocervical fixation using two C2 laminar screws. METHODS: Four children with MPS IVA underwent decompression and C0-C2 instrumented fusion using two C2 bilateral laminar screws. The dimensions of the C2 lamina were measured. Clinical and radiological results were monitored prospectively for a minimum 3 years. RESULTS: The mean laminar length was 24 ± 1.15 mm, width 6.15 ± 0.55 mm and height 7.4 ± 0.6 mm. Patients remained in a stable neurological condition. The mean antero-posterior diameter of the spinal canal on the pre-operative MR was 6.2 ± 0.74 mm and it was enlarged to 11.4 ± 0.8 mm after 3 years. All screws were placed adequately. In all patients, the control CT scan 2 years post-operatively revealed a stable position of the treated segments, but solid bony fusion was not registered in any patient. CONCLUSIONS: Decompression and fusion of the upper cervical spine is a generally accepted approach to treat upper cervical spine instability and myelopathy in MPS IVA patients. The feasibility and the suitability of the technique of C0-C2 stabilization using bilateral C2 laminar screws have been presented.
Department of Pediatric Neurosurgery Thomayer's Teaching Hospital Prague Czech Republic
Department of Pediatric Surgery and Traumatology Thomayer's Teaching Hospital Prague Czech Republic
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