Drug fever as an adverse effect of acitretin in complicated psoriasis patient
Language English Country United States Media print-electronic
Document type Case Reports, Journal Article
PubMed
26133643
DOI
10.1111/dth.12263
Knihovny.cz E-resources
- Keywords
- acitretin, adverse drug reaction, drug fever, psoriasis, systemic retinoids,
- MeSH
- Acitretin adverse effects MeSH
- Fever chemically induced diagnosis MeSH
- Keratolytic Agents adverse effects MeSH
- Middle Aged MeSH
- Humans MeSH
- Drug Substitution MeSH
- Psoriasis diagnosis drug therapy MeSH
- Treatment Outcome MeSH
- Check Tag
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Publication type
- Journal Article MeSH
- Case Reports MeSH
- Names of Substances
- Acitretin MeSH
- Keratolytic Agents MeSH
We present a case of a 63-year old man with severe chronic plaque psoriasis and a recent history of lung cancer, wherein fever appeared suddenly after initiation of treatment with low dose acitretin. Tumor recurrence or infection was not found during extensive examinations, nevertheless the patient was empirically treated with broad-spectrum antibiotics without any effect on fever. Immediately after discontinuation of acitretin therapy, the fever disappeared. The patient was followed for next 2 years, during this period similar problems did not reappear, although there has been a relapse of psoriasis and the patient was switched later on biological treatment.
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