Dengue fever in Czech travellers: A 10-year retrospective study in a tertiary care centre
Language English Country Netherlands Media print-electronic
Document type Journal Article
PubMed
26159629
DOI
10.1016/j.tmaid.2015.06.005
PII: S1477-8939(15)00106-4
Knihovny.cz E-resources
- Keywords
- Arthropod-borne viruses, Dengue, Fever, Travel-acquired infections, Travellers,
- MeSH
- Acute Disease MeSH
- Time Factors MeSH
- Tertiary Care Centers * MeSH
- Travel * MeSH
- Dengue diagnosis epidemiology prevention & control virology MeSH
- Adult MeSH
- Fever MeSH
- Hospitalization MeSH
- Humans MeSH
- Retrospective Studies MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Male MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Geographicals
- Asia epidemiology MeSH
- Czech Republic epidemiology MeSH
- Asia, Southeastern epidemiology MeSH
BACKGROUND: Dengue fever is a frequent cause of morbidity in travellers. The objective was to describe the epidemiological and clinical characteristics of dengue fever in Czech travellers. METHOD: This descriptive study includes patients with acute dengue fever diagnosed at Hospital Na Bulovce during 2004-2013. Data were collected and analysed retrospectively. RESULTS: A total of 132 patients (83 males and 49 females) of median age 33 years (IQR 29-40) were included. Diagnosis was established by NS1 antigen detection in 87/107 cases (81.3%) and/or RT-PCR in 50/72 (69.4%) and by serology in 25 cases (18.9%). Dengue was acquired in South-East Asia in 69 cases (52.3%), followed by South Asia (48 cases; 36.3%), Latin America (14; 10.6%) and Sub-Saharan Africa (1; 0.8%). The most frequent symptoms included fever, rash and headache. Initial leukocyte and lymphocyte counts were lower in patients who presented in the early phase (0-4 days), however, platelet count was lower and AST, ALT and LDH activity higher in patients with a longer symptoms duration (≥5 days). The clinical course was mostly uncomplicated. CONCLUSIONS: Dengue fever is becoming a frequent cause of fever in Czech travellers. Clinicians should be familiar with the typical clinical findings and novel diagnostic methods.
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