Recent developments and applications of capillary and microchip electrophoresis in proteomic and peptidomic analyses
Language English Country Germany Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
- Keywords
- Capillary electrophoresis, Mass spectrometry, Microchip Electrophoresis, Peptidomics, Proteomics,
- MeSH
- Electrophoresis, Capillary methods trends MeSH
- Electrophoresis, Microchip methods trends MeSH
- Humans MeSH
- Peptides chemistry MeSH
- Proteins chemistry MeSH
- Proteomics methods MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- Names of Substances
- Peptides MeSH
- Proteins MeSH
This review presents recent developments and applications of capillary and microchip electromigration methods in proteomics and peptidomics. Sample preparation methods as well as instrumental innovations in the coupling of these advanced electromigration methods with mass spectrometry detection employed in proteomic and peptidomic analyses are presented. Interesting applications of various capillary electromigration methods in bottom-up as well as top-down proteomics, including investigation of post-translational modifications of proteins are described. In addition, several examples of the use of capillary electromigration methods combined with mass spectrometry detection in clinical proteomics and peptidomics are demonstrated.
References provided by Crossref.org
Peptidomics and Capillary Electrophoresis
