Early colonization of the oral cavity in 6- and 12-month-old infants by cariogenic and periodontal pathogens: a case-control study
Language English Country United States Media print-electronic
Document type Journal Article
PubMed
26914065
DOI
10.1007/s12223-016-0453-z
PII: 10.1007/s12223-016-0453-z
Knihovny.cz E-resources
- MeSH
- Aggregatibacter actinomycetemcomitans isolation & purification MeSH
- Bacterial Load MeSH
- Fusobacterium nucleatum isolation & purification MeSH
- Infant MeSH
- Humans MeSH
- Microbiota * MeSH
- Polymerase Chain Reaction MeSH
- Risk Factors MeSH
- Saliva microbiology MeSH
- Streptococcus mutans isolation & purification MeSH
- Case-Control Studies MeSH
- Mouth microbiology MeSH
- Age Factors MeSH
- Check Tag
- Infant MeSH
- Humans MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
The colonization of the oral cavity by cariogenic and periodontal pathogens occurs earlier than previously thought. This study aimed to identify the presence and quantity of representative cariogenic and periodontal pathogens in the oral cavities of 6- and 12-month olds and to evaluate the influence of C-section delivery on early Streptococcus mutans (Sm) colonization of the oral cavity. The research cohort was composed of 59 infants (35 infants were delivered vaginally and 24 via C-section) and their mothers. At 6 months of age, the infants were examined, and unstimulated saliva samples were collected. Variables concerning mothers were DMF index and salivary levels of Sm. Repeated saliva samples were taken 6 months later. The representative cariogenic and periodontal microorganisms were identified, and their quantities were measured using a polymerase chain reaction-based method. The relationships between the presence of detected microbes, the mode of delivery, and maternal variables were evaluated using paired t tests, chi-squared test, and ANOVAs. High rates of cariogenic bacteria, Aggregatibacter actinomycetemcomitans (Aa) and Fusobacterium nucleatum (Fn), were found in both infant cohorts. An analysis of the differences between delivery methods revealed that the group of 6-month-old vaginally delivered infants had a significantly higher amount of Sm. We conclude that the cariogenic bacteria, Aa and Fn, are present in edentulous infants. This presence increases in the months following the eruption of the deciduous teeth. Results did not confirm the influence of C-section delivery on the early Sm colonization of the oral cavity.
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