Clinically meaningful blood pressure reductions with low intensity isometric handgrip exercise. A randomized trial
Language English Country Czech Republic Media print-electronic
Document type Comparative Study, Journal Article, Randomized Controlled Trial
PubMed
27070747
DOI
10.33549/physiolres.933120
PII: 933120
Knihovny.cz E-resources
- MeSH
- Adult MeSH
- Hypertension therapy MeSH
- Isometric Contraction * MeSH
- Blood Pressure * MeSH
- Middle Aged MeSH
- Humans MeSH
- Hand Strength physiology MeSH
- Heart Rate MeSH
- Exercise Therapy * MeSH
- Healthy Volunteers MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Randomized Controlled Trial MeSH
- Comparative Study MeSH
There exists no examination of what is the minimum anti-hypertensive threshold intensity for isometric exercise training. Twenty two normotensive participants were randomly assigned to training intensities at either 5 % or 10 % of their maximal contraction. Twenty participants completed the study. Clinical meaningful, but not statistically significant, reductions in systolic blood pressure were observed in both 5 % and 10 % groups -4.04 mm Hg (95 % CI -8.67 to +0.59, p=0.08) and -5.62 mm Hg (95 % CI -11.5 to +0.29, p=0.06) respectively after 6 weeks training. No diastolic blood pressure reductions were observed in either 5 % -0.97 mm Hg (95 % CI -2.56 to +0.62, p=0.20) or 10 % MVC +1.8 mm Hg (95 % CI -1.29 to +4.89, p=0.22) groups respectively after training. In those unable to complete isometric exercise at the traditional 30 % intensity, our results suggest there is no difference between 5 and 10 % groups and based on the principle of regression to the mean, this could mean both interventions induce a similar placebo-effect.
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