Hypertrophic obstructive cardiomyopathy
Language English Country England, Great Britain Media print-electronic
Document type Journal Article, Review
PubMed
27912983
DOI
10.1016/s0140-6736(16)31321-6
PII: S0140-6736(16)31321-6
Knihovny.cz E-resources
- MeSH
- Echocardiography MeSH
- Genetic Counseling MeSH
- Genetic Testing methods MeSH
- Cardiomyopathy, Hypertrophic diagnosis epidemiology etiology therapy MeSH
- Humans MeSH
- Magnetic Resonance Imaging MeSH
- Death, Sudden, Cardiac etiology prevention & control MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
Hypertrophic obstructive cardiomyopathy is an inherited myocardial disease defined by cardiac hypertrophy (wall thickness ≥15 mm) that is not explained by abnormal loading conditions, and left ventricular obstruction greater than or equal to 30 mm Hg. Typical symptoms include dyspnoea, chest pain, palpitations, and syncope. The diagnosis is usually suspected on clinical examination and confirmed by imaging. Some patients are at increased risk of sudden cardiac death, heart failure, and atrial fibrillation. Patients with an increased risk of sudden cardiac death undergo cardioverter-defibrillator implantation; in patients with severe symptoms related to ventricular obstruction, septal reduction therapy (myectomy or alcohol septal ablation) is recommended. Life-long anticoagulation is indicated after the first episode of atrial fibrillation.
References provided by Crossref.org
Genetic Testing in Patients with Hypertrophic Cardiomyopathy
Head-Up Tilt Test in Risk Stratification of Patients with Hypertrophic Cardiomyopathy
