NewProt - a protein engineering portal
Language English Country England, Great Britain Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
28475759
DOI
10.1093/protein/gzx024
PII: 3799702
Knihovny.cz E-resources
- Keywords
- mutant analysis, portal, protein design, protein engineering, web server,
- MeSH
- Databases, Protein * MeSH
- Internet * MeSH
- Models, Molecular MeSH
- Protein Engineering methods MeSH
- Proteins * chemistry genetics metabolism MeSH
- Software * MeSH
- User-Computer Interface MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Proteins * MeSH
The NewProt protein engineering portal is a one-stop-shop for in silico protein engineering. It gives access to a large number of servers that compute a wide variety of protein structure characteristics supporting work on the modification of proteins through the introduction of (multiple) point mutations. The results can be inspected through multiple visualizers. The HOPE software is included to indicate mutations with possible undesired side effects. The Hotspot Wizard software is embedded for the design of mutations that modify a proteins' activity, specificity, or stability. The NewProt portal is freely accessible at http://newprot.cmbi.umcn.nl/ and http://newprot.fluidops.net/.
Bio Prodict B 5 NieuweMarktstraat 54e 6511 AA Nijmegen The Netherlands
CMBI Radboud University Medical Centre Geert Grooteplein Zuid 26 28 6525 GA Nijmegen The Netherlands
Enantis INBIT Kamenice 34 625 00 Brno Czech Republic
Fluid Operations AG Altrottstraße 31 69190 Walldorf Germany
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