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Article

PubMed

This record comes from PubMed

Occurrence of Anaemia in the First Year of Inflammatory Bowel Disease in a European Population-based Inception Cohort-An ECCO-EpiCom Study

Journal of Crohn's & colitis. 2017 Oct 01 ; 11 (10) : 1213-1222.

J Crohns Colitis
ISSN 1876-4479 | 1873-9946
Source

Language English Country Great Britain, England Media print

Document type Journal Article, Multicenter Study

Persistent link https://www.medvik.cz/link/pmid28575481

PubMed 28575481
DOI 10.1093/ecco-jcc/jjx077
PII: 3859627
Knihovny.cz E-resources

Keywords
anaemia, inflammatory bowel disease, prevalence,
MeSH
Anemia diagnosis epidemiology etiology MeSH
Crohn Disease complications MeSH
Adult MeSH
Inflammatory Bowel Diseases complications MeSH
Middle Aged MeSH
Humans MeSH
Adolescent MeSH
Young Adult MeSH
Prospective Studies MeSH
Aged, 80 and over MeSH
Aged MeSH
Colitis, Ulcerative complications MeSH
Check Tag
Adult MeSH
Middle Aged MeSH
Humans MeSH
Adolescent MeSH
Young Adult MeSH
Male MeSH
Aged, 80 and over MeSH
Aged MeSH
Female MeSH
Publication type
Journal Article MeSH
Multicenter Study MeSH

BACKGROUND AND AIMS: Anaemia is an important complication of inflammatory bowel disease [IBD]. The aim of this study was to determine the prevalence of anaemia and the practice of anaemia screening during the first year following diagnosis, in a European prospective population-based inception cohort. METHODS: Newly diagnosed IBD patients were included and followed prospectively for 1 year in 29 European and one Australian centre. Clinical data including demographics, medical therapy, surgery and blood samples were collected. Anaemia was defined according to the World Health Organization criteria. RESULTS: A total of 1871 patients (Crohn's disease [CD]: 686, 88%; ulcerative colitis [UC]: 1,021, 87%; IBD unclassified [IBDU] 164. 81%) were included in the study. The prevalence of anaemia was higher in CD than in UC patients and, overall, 49% of CD and 39% of UC patients experienced at least one instance of anaemia during the first 12 months after diagnosis. UC patients with more extensive disease and those from Eastern European countries, and CD patients with penetrating disease or colonic disease location, had higher risks of anaemia. CD and UC patients in need of none or only mild anti-inflammatory treatment had a lower risk of anaemia. In a significant proportion of patients, anaemia was not assessed until several months after diagnosis, and in almost half of all cases of anaemia a thorough work-up was not performed. CONCLUSIONS: Overall, 42% of patients had at least one instance of anaemia during the first year following diagnosis. Most patients were assessed for anaemia regularly; however, a full anaemia work-up was frequently neglected in this community setting.

1st Department of Medicine Semmelweis University Budapest Hungary

1st Division of Internal Medicine and Hepato Gastroenterology Unit University Hospital Ioannina Greece

Center for Digestive Diseases Karolinska University Hospital Stockholm Sweden

Center for Quality Region of Southern Denmark Denmark

Clinic of Gastroenterology University of Medicine 'Victor Babes' Timisoara Romania

Department of Gastroenterology Adelaide and Meath Hospital TCD Dublin Ireland

Department of Gastroenterology and Alimentary Tract Surgery Tampere University Hospital Tampere Finland

Department of Gastroenterology and Hepatology Soroka Medical Center and Ben Gurion University of the Negev Beer Sheva Israel

Department of Gastroenterology Faculty of Medicine and Health Örebro University Örebro Sweden

Department of Gastroenterology Herlev Univerisity Hospital Herlev Denmark

Department of Gastroenterology Hospital de São João Porto Portugal

Department of Gastroenterology Instituto de Investigación Sanitaria Galicia Sur Estrutura Organizativa de Xestión Integrada de Vigo Vigo Spain