Cell-compatible conducting polyaniline films prepared in colloidal dispersion mode
Language English Country Netherlands Media print-electronic
Document type Journal Article
PubMed
28601759
DOI
10.1016/j.colsurfb.2017.05.066
PII: S0927-7765(17)30333-8
Knihovny.cz E-resources
- Keywords
- Cell compatibility, Colloidal dispersions, Conducting films, Polyaniline, Skin irritation, Surface analysis,
- MeSH
- Aniline Compounds adverse effects chemistry MeSH
- Fibroblasts drug effects MeSH
- Colloids adverse effects chemistry MeSH
- Membranes, Artificial * MeSH
- Mice MeSH
- Spectroscopy, Fourier Transform Infrared MeSH
- Cell Survival drug effects MeSH
- Animals MeSH
- Check Tag
- Mice MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Aniline Compounds MeSH
- Colloids MeSH
- Membranes, Artificial * MeSH
- polyaniline MeSH Browser
Conducting polyaniline can be prepared and modified using several procedures, all of which can significantly influence its applicability in different fields of biomedicine or biotechnology. The modifications of surface properties are crucial with respect to the possible applications of this polymer in tissue engineering or as biosensors. Innovative technique for preparing polyaniline films via in-situ polymerization in colloidal dispersion mode using four stabilizers (poly-N-vinylpyrrolidone; sodium dodecylsulfate; Tween 20 and Pluronic F108) was developed. The surface energy, conductivity, spectroscopic features, and cell compatibility of thin polyaniline films were determined using contact-angle measurement, the van der Pauw method, Fourier-transform infrared spectroscopy, and assay conducted on mouse fibroblasts, respectively. The stabilizers significantly influenced not only the surface and electrical properties of the films but also their cell compatibility. Sodium dodecylsulfate seems preferentially to combine both the high conductivity and good cell compatibility. Moreover, the films with sodium dodecylsulfate were non-irritant for skin, which was confirmed by their in-vitro exposure to the 3D-reconstructed human tissue model.
Centre of Polymer Systems Tomas Bata University in Zlin 76001 Zlin Czech Republic
Department of Surface Engineering Plasma Laboratory Josef Stefan Institute 1000 Ljubljana Slovenia
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