Case study: Reinforcement of 45S5 bioglass robocast scaffolds by HA/PCL nanocomposite coatings
Language English Country Netherlands Media print-electronic
Document type Journal Article
PubMed
28709035
DOI
10.1016/j.jmbbm.2017.07.012
PII: S1751-6161(17)30298-9
Knihovny.cz E-resources
- Keywords
- 45S5 BG scaffolds, Coating, HA nanoparticles, Mechanical properties,
- MeSH
- Durapatite analysis MeSH
- Ceramics analysis MeSH
- Nanocomposites analysis MeSH
- Polyesters MeSH
- Glass analysis MeSH
- Materials Testing MeSH
- Tissue Engineering MeSH
- Tissue Scaffolds * MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- bioactive glass 45S5 MeSH Browser
- Durapatite MeSH
- polycaprolactone MeSH Browser
- Polyesters MeSH
The purpose of this study is to analyze the mechanical enhancement provided by nanocomposite coatings deposited on robocast 45S5 bioglass (BG) scaffolds for bone tissue regeneration. In particular, a nanocomposite layer consisting of hydroxyapatite (HA) nanoparticles, as reinforcing phase, in a polycaprolactone (PCL) matrix was deposited onto the surface of the BG struts conforming the scaffold. Three different HA nanopowders were used in this study. The effect of particle size and morphology of these HA nanopowders on the mechanical performance of 45S5 BG scaffolds is evaluated.
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