The rise of the mosquitoes-transmitted diseases, like dengue, zika and chikungunya in Brazil in the last years has increased concerns on protection against mosquitoes bites. However, the prohibitive prices of the commercially available repellents for the majority of the Brazilian population has provoked a search for cheaper solutions, like the use of the homemade ethanolic extract of Indian clove (Syzygium aromaticum L.) as repellent, which has been reported as quite efficient by the local press. In order to verify this, we performed here the quantification of the main components of this extract through high-performance thin-layer chromatography (HPTLC)-densitometry and evaluated its efficiency as a repellent and its acetylcholinesterase (AChE) inhibition capacity. Our results have proved HPTLC-densitometry as an efficient and appropriate method for this quantification and confirmed the repellency activity, as well as its capacity of AChE inhibition.

Anhanguera College of Brasília Brazil

Biodiversity Chemistry Laboratory Phytomedicine Agroecological Platform Brazil

Center for Basic and Applied Research Faculty of Informatics and Management University of Hradec Kralove Hradec Kralove Czech Republic

Laboratory of Molecular Modeling Applied to the Chemical and Biological Defense Military Institute of Engineering Rio de Janeiro Brazil

National Institute of Intellectual Property Brazil

University Hospital Biomedical Research Centre Sokolska 581 500 05 Hradec Kralove Czech Republic

University Hradec Kralove Faculty of Science Department of Chemistry Rokitanskeho 62 50003 Hradec Kralove Czech Republic

University of Brasília University of Brasilia Nucleus of tropical medicine Brazil

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