Vitamin D, neurosteroids and autism
Language English Country Czech Republic Media print
Document type Journal Article, Review
PubMed
28948817
DOI
10.33549/physiolres.933721
PII: 933721
Knihovny.cz E-resources
- MeSH
- Autistic Disorder drug therapy etiology metabolism MeSH
- Epigenesis, Genetic drug effects physiology MeSH
- Humans MeSH
- Brain drug effects metabolism MeSH
- Vitamin D Deficiency complications drug therapy metabolism MeSH
- Neurotransmitter Agents metabolism therapeutic use MeSH
- Vitamin D metabolism therapeutic use MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
- Names of Substances
- Neurotransmitter Agents MeSH
- Vitamin D MeSH
Vitamin D had been for a long time investigated for its effects on bone metabolism. Recently has been observed that the incidence of some neurodevelopmental disorders (including autism) increases hand in hand with vitamin D deficiency. Indeed, vitamin D was reported to modulate the biosynthesis of neurotransmitters and neurotrophic factors; moreover, its receptor was found in the central nervous system. Vitamin D deficiency was therefore assessed as a risk factor for autism, however the biological mechanism has not yet been revealed. In our review we focused on potential connections among vitamin D, steroids and autism. Potential mechanisms of vitamin D action are also discussed.
References provided by Crossref.org
Alternations in the Cardiovascular Autonomic Regulation and Growth Factors in Autism
