Cancer and heart failure (HF) are common medical conditions with a steadily rising prevalence in industrialized countries, particularly in the elderly, and they both potentially carry a poor prognosis. A new diagnosis of malignancy in subjects with pre-existing HF is not infrequent, and challenges HF specialists as well as oncologists with complex questions relating to both HF and cancer management. An increased incidence of cancer in patients with established HF has also been suggested. This review paper summarizes the epidemiology and the prognostic implications of cancer occurrence in HF, the impact of pre-existing HF on cancer treatment decisions and the impact of cancer on HF therapeutic options, while providing some practical suggestions regarding patient care and highlighting gaps in knowledge.

1st Department of Medicine Cardioangiology Medical Faculty and University Hospital Hradec Kralove Czech Republic

Belgrade University Medical Center Belgrade Serbia

Cardio Oncology Clinic Heart Failure Unit Department of Cardiology Athens University Hospital 'Attikon' National and Kapodistrian University of Athens Athens Greece

Cardio Oncology Unit Cardiac Imaging Unit Department of Cardiology La Paz University Hospital IdiPAz Madrid Spain

Cardiology Research Institute Moscow Russia

Department of Cardiology at Charité University Medicine Berlin Germany

Department of Cardiology Cardio Oncology Bern University Hospital Bern Switzerland

Department of Cardiology Department of Research and Education General Hospital Celje Celje Slovenia Faculty of Medicine University of Ljubljana Ljubljana Slovenia

Department of Cardiology Lariboisière Hospital Paris France; U942 INSERM BIOCANVAS Paris France; Department of Cardiology University of Paris 7 Denis Diderot Paris France

Department of Cardiology Medical University of Vienna Vienna Austria

Department of Cardiology University of Groningen University Medical Center Groningen Groningen The Netherlands

Department of Clinical and Experimental Medicine Flaviano Magrassi Luigi Vanvitelli University of Campania Naples Italy

Department of Internal Medicine University of Genova; and Cardiology Unit IRCCS Policlinic Hospital San Martino Genova Italy

Department of Translational Medical Sciences Federico 2 University Naples Italy

Klinik für Kardiologie und Pneumologie Herzzentrum Göttingen Universitätsmedizin Göttingen Georg August Universität Göttingen Germany; Deutsches Zentrum für Herz und Kreislaufforschung Standort Göttingen Göttingen Germany

Monash University Australia and University of Warwick UK

Royal Brompton Hospital and Imperial College London UK

University Heart Center University Hospital Zurich Zurich Switzerland

Citace poskytuje Crossref.org

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