BACKGROUND AND AIMS: The frequency and timing of meals may affect cardiovascular health (CVH) outcomes, but large-scale epidemiological studies are lacking. The aim of this study was to understand the relationship between eating time interval and frequency, and measures of ideal CVH in the Kardiovize Brno cohort study, a random urban sample population in Central Europe. METHODS AND RESULTS: 1659 members of the Kardiovize Brno 2030 cohort were included in a cross-sectional study (mean age = 46.86 years; 44.6% male). Exposure variables were eating time interval and frequency, and skipping meals. Primary outcomes were indices of CVH, including body mass index, diet, physical activity, smoking, blood pressure, glucose and cholesterol, and the composite CVH score. Cluster analysis and binary logistic regression analysis were used to evaluate eating habits and the association between variables. After adjustment for well-known risk factors, subjects who skipped breakfast or the afternoon snack had a higher risk of poor CVH (OR = 1.613; 95%CI = 1.121-2.320; p = 0.010; OR = 1.409; 95%CI = 1.110-1.788; p = 0.005, respectively). Moreover, we identified three clusters of individuals based on eating habits; from cluster 1 to cluster 3, eating time interval and frequency increased and this was associated with increases in CVH score from 8.70 (SEM = 0.10) in cluster 1, and 9.06 (SEM = 0.08) in cluster 2 to 9.42 (SEM = 0.09) in cluster 3 (p-trend = 0.019). CONCLUSIONS: Our findings suggest that skipping breakfast or the afternoon snack are risk factors for poor CVH, while higher eating time interval and frequency may promote ideal CVH.

Department of Cardiovascular Medicine Division of Preventive Cardiology Mayo Clinic Rochester MN USA

Department of Medical and Surgical Sciences and Advanced Technologies GF Ingrassia University of Catania Catania Italy

International Clinical Research Center St Anne's University Hospital Brno Czech Republic

International Clinical Research Center St Anne's University Hospital Brno Czech Republic; Department of Medical and Surgical Sciences and Advanced Technologies GF Ingrassia University of Catania Catania Italy

International Clinical Research Center St Anne's University Hospital Brno Czech Republic; Division of Medicine University College London London UK

Citace poskytuje Crossref.org

Lipidomic Profiling Identifies Signatures of Poor Cardiovascular Health

Is Drinking Alcohol Really Linked to Cardiovascular Health? Evidence from the Kardiovize 2030 Project

Determinants of Metabolic Health Across Body Mass Index Categories in Central Europe: A Comparison Between Swiss and Czech Populations

The Effects of Meal Timing and Frequency, Caloric Restriction, and Fasting on Cardiovascular Health: an Overview

Obesity-induced nucleosome release predicts poor cardio-metabolic health

How dietary patterns affect left ventricular structure, function and remodelling: evidence from the Kardiovize Brno 2030 study

Dog Ownership and Cardiovascular Health: Results From the Kardiovize 2030 Project

Independent Effects of Hypertension and Obesity on Left Ventricular Mass and Geometry: Evidence from the Cardiovision 2030 Study

Sleep Duration and Excessive Daytime Sleepiness Are Associated with Obesity Independent of Diet and Physical Activity

Association of Dietary Patterns with Metabolic Syndrome: Results from the Kardiovize Brno 2030 Study