Visible to NIR Light Photoactivation of Hydrogen Sulfide for Biological Targeting
Language English Country United States Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
- MeSH
- Biosynthetic Pathways MeSH
- Cell Tracking MeSH
- Hep G2 Cells MeSH
- Photochemical Processes * MeSH
- Carbonic Anhydrases chemistry MeSH
- Catalysis MeSH
- Humans MeSH
- Optical Imaging MeSH
- Sulfur Oxides chemistry MeSH
- Boron Compounds chemistry MeSH
- Hydrogen Sulfide chemistry MeSH
- Light MeSH
- Thiocarbamates chemistry MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene MeSH Browser
- carbonyl sulfide MeSH Browser
- Carbonic Anhydrases MeSH
- Sulfur Oxides MeSH
- Boron Compounds MeSH
- Hydrogen Sulfide MeSH
- Thiocarbamates MeSH
The synthesis and photochemical properties of H2S-releasing BODIPY thiocarbamate photocage scaffolds activatable by visible-to-NIR (up to 700 nm) light to release carbonyl sulfide (COS), which is transformed to H2S using either isolated or natural carbonic anhydrase, is reported. The excellent uncaging cross section and high H2S release yields in in vitro experiments, including live-cell imaging, suggest that these photocages can serve as a platform for the bio-orthogonal phototriggered release within the tissue-transparent window.
References provided by Crossref.org
Sulfonothioated meso-Methyl BODIPY Shows Enhanced Uncaging Efficiency and Releases H2Sn
Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials
