Antiviral potentials of Lactobacillus plantarum, Lactobacillus amylovorus, and Enterococcus hirae against selected Enterovirus
Jazyk angličtina Země Spojené státy americké Médium print-electronic
Typ dokumentu časopisecké články
PubMed
30267215
DOI
10.1007/s12223-018-0648-6
PII: 10.1007/s12223-018-0648-6
Knihovny.cz E-zdroje
- MeSH
- antivirové látky farmakologie MeSH
- druhová specificita MeSH
- Enterococcus hirae fyziologie MeSH
- enterovirové infekce prevence a kontrola virologie MeSH
- Enterovirus klasifikace účinky léků MeSH
- Lactobacillales fyziologie MeSH
- Lactobacillus acidophilus fyziologie MeSH
- Lactobacillus plantarum fyziologie MeSH
- lidé MeSH
- nádorové buněčné linie MeSH
- probiotika farmakologie MeSH
- viabilita buněk MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- antivirové látky MeSH
Enteroviruses have been associated with a host of clinical presentations including acute flaccid paralysis (AFP). The site of primary replication for most enteroviruses is the gastrointestinal tract (GIT) and lactic acid bacteria (LAB) may confer protection in the GIT against them. This study therefore investigates the antiviral potential of some selected lactic acid bacteria against enterovirus isolates recovered from AFP cases. The antiviral activities of Lactobacillus plantarum, Lactobacillus amylovorus, and Enterococcus hirae in broth culture, their cell-free supernatant (CFS), and bacterial cell pellets were assayed against Echovirus 7 (E7), E13, and E19 in a pre- and post-treatment approach using cytopathic effect (CPE) and cell viability (MTT) assay. The tested Lactobacillus plantarum, Lactobacillus amylovorus, and Enterococcus hirae strains have good antiviral properties against E7 and E19 but not against E13. Lactobacillus amylovorus AA099 shows the highest activity against E19. The pre-treatment approach displays better antiviral activities compared to post-treatment approach. The LAB in broth suspension have better antiviral activities than their corresponding CFS and bacterial pellet. Lactic acid bacteria used in this study have the potential as antiviral agents.
Department of Pharmacognosy Faculty of Pharmacy University of Ibadan Ibadan Oyo State Nigeria
Department of Virology University College Hospital University of Ibadan Ibadan Oyo State Nigeria
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PLoS One. 2011 Mar 18;6(3):e18022 PubMed
Int J Food Microbiol. 2011 May 27;147(2):97-104 PubMed
Braz J Infect Dis. 2012 Mar-Apr;16(2):129-35 PubMed
Infect Genet Evol. 2013 Mar;14:282-93 PubMed
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