Was the Mitochondrion Necessary to Start Eukaryogenesis?
Language English Country England, Great Britain Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
PubMed
30466901
DOI
10.1016/j.tim.2018.10.005
PII: S0966-842X(18)30214-2
Knihovny.cz E-resources
- Keywords
- eukaryogenesis, eukaryotic anaerobes, last eukaryotic common ancestor, mitochondrion, phagocytosis,
- MeSH
- Adenosine Triphosphate MeSH
- Archaea physiology MeSH
- Biological Evolution * MeSH
- Eukaryota genetics physiology MeSH
- Eukaryotic Cells physiology MeSH
- Phagocytosis MeSH
- Genome MeSH
- Mitochondria genetics physiology MeSH
- Prokaryotic Cells physiology MeSH
- Symbiosis MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- Names of Substances
- Adenosine Triphosphate MeSH
Arguments based on cell energetics favour the view that a mitochondrion capable of oxidative phosphorylation was a prerequisite for the evolution of other features of the eukaryotic cell, including increased volume, genome size and, eventually, phagotrophy. Contrary to this we argue that: (i) extant amitochondriate eukaryotes possess voluminous phagotrophic cells with large genomes; (ii) picoeukaryotes demonstrate that phagotrophy is feasible at prokaryotic cell sizes; and (iii) the assumption that evolution of complex features requires extra ATP, often mentioned in this context, is unfounded and should not be used in such considerations. We claim that the diversity of cell organisations and functions observed today in eukaryotes gives no reason to postulate that a mitochondrion must have preceded phagocytosis in eukaryogenesis.
Department of Parasitology Faculty of Science Charles University BIOCEV Vestec 252 50 Czech Republic
Department of Zoology Faculty of Science Charles University Prague 128 43 Czech Republic
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