Current treatment of behavioral and cognitive symptoms of Parkinson's disease
Language English Country Great Britain, England Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
PubMed
30852149
DOI
10.1016/j.parkreldis.2019.02.042
PII: S1353-8020(19)30087-2
Knihovny.cz E-resources
- Keywords
- Apathy, Behavioral, Cognitive, Dementia, Dopaminergic, Impulse control disorders, Mild cognitive impairment, Parkinson's disease, Psychosis, treatment,
- MeSH
- Apathy * MeSH
- Dementia drug therapy etiology therapy MeSH
- Disruptive, Impulse Control, and Conduct Disorders drug therapy etiology therapy MeSH
- Cognitive Dysfunction drug therapy etiology therapy MeSH
- Humans MeSH
- Parkinson Disease complications drug therapy therapy MeSH
- Psychotic Disorders drug therapy etiology therapy MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
Cognitive and behavioral symptoms are common in Parkinson's disease, may occur even in the prodromal stages of the disease, worsen with disease progression, and surpass motor symptoms as the major factors affecting patient quality of life and caregiver burden. The symptoms may be caused by the disease pathology or they may represent adverse effects of treatment, or both etiological factors may contribute. Although many of these symptoms are related to dopaminergic dysfunction or dopaminergic medication, other neurotransmitters are involved as well. Behavioral symptoms including impulse control disorders, apathy, psychosis, as well as mild cognitive impairment and dementia are reviewed with a special focus on current treatment approaches.
References provided by Crossref.org
Non-invasive brain stimulation: current and future applications in neurology
