Mosquito adaptations to hematophagia impact pathogen transmission
Jazyk angličtina Země Nizozemsko Médium print-electronic
Typ dokumentu časopisecké články, Research Support, N.I.H., Extramural, přehledy
Grantová podpora
R01 AI045545
NIAID NIH HHS - United States
PubMed
31247413
DOI
10.1016/j.cois.2019.02.002
PII: S2214-5745(18)30141-X
Knihovny.cz E-zdroje
- MeSH
- Culicidae mikrobiologie fyziologie MeSH
- fyziologická adaptace * MeSH
- komáří přenašeči mikrobiologie fyziologie MeSH
- přijímání potravy MeSH
- stravovací zvyklosti MeSH
- trávení MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
- Research Support, N.I.H., Extramural MeSH
Mosquito-borne diseases such as Dengue fever, Chikungunya, and Malaria are critical threats to public health in many parts of the world. Female mosquitoes have evolved multiple adaptive mechanisms to hematophagy, including the ability to efficiently draw and digest blood, as well as the ability to eliminate excess fluids and toxic by-products of blood digestion. Pathogenic agents enter the mosquito digestive tract with the blood meal and need to travel through the midgut and into the hemocele in order to reach the salivary glands and infect a new host. Pathogens need to adjust to these hostile gut, hemocele, and salivary gland environments, and when possible influence the physiology and behavior of their hosts to enhance transmission.
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