Mosquito adaptations to hematophagia impact pathogen transmission

. 2019 Aug ; 34 () : 21-26. [epub] 20190212

Jazyk angličtina Země Nizozemsko Médium print-electronic

Typ dokumentu časopisecké články, Research Support, N.I.H., Extramural, přehledy

Perzistentní odkaz   https://www.medvik.cz/link/pmid31247413

Grantová podpora
R01 AI045545 NIAID NIH HHS - United States

Odkazy

PubMed 31247413
DOI 10.1016/j.cois.2019.02.002
PII: S2214-5745(18)30141-X
Knihovny.cz E-zdroje

Mosquito-borne diseases such as Dengue fever, Chikungunya, and Malaria are critical threats to public health in many parts of the world. Female mosquitoes have evolved multiple adaptive mechanisms to hematophagy, including the ability to efficiently draw and digest blood, as well as the ability to eliminate excess fluids and toxic by-products of blood digestion. Pathogenic agents enter the mosquito digestive tract with the blood meal and need to travel through the midgut and into the hemocele in order to reach the salivary glands and infect a new host. Pathogens need to adjust to these hostile gut, hemocele, and salivary gland environments, and when possible influence the physiology and behavior of their hosts to enhance transmission.

Citace poskytuje Crossref.org

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