Effects of food-borne ZnO nanoparticles on intestinal microbiota of common carp (Cyprinus carpio L.)
Language English Country Germany Media print-electronic
Document type Journal Article
Grant support
CENAKVA (No. CZ.1.05/2.1.00/01.0024) and CENAKVA II (No. LO1205 under the NPU I program)
Ministerstvo Školství, Mládeže a Tělovýchovy (CZ)
PubMed
31273654
DOI
10.1007/s11356-019-05616-x
PII: 10.1007/s11356-019-05616-x
Knihovny.cz E-resources
- Keywords
- Common carp, Intestine, Microbiome, Nanoparticles, ZnO,
- MeSH
- Carps MeSH
- Microbiota MeSH
- Nanoparticles MeSH
- Zinc Oxide chemistry pharmacology MeSH
- Food MeSH
- RNA, Ribosomal, 16S chemistry MeSH
- Intestines physiology MeSH
- Gastrointestinal Microbiome drug effects MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Zinc Oxide MeSH
- RNA, Ribosomal, 16S MeSH
Ingestion of nanoparticles (NPs) with antimicrobial properties may disrupt the balance of intestinal microbiota. To investigate the effects of zinc oxide (ZnO) NPs on intestinal flora, common carp Cyprinus carpio were fed a commercial feed containing 500 mg kg-1 ZnO NPs for 6 weeks and compared to a control group receiving a similar feed-only regime. Sequencing data were analyzed both in individual fish and in pooled samples. Sequencing of 16S rRNA encoding gene of individual specimens revealed high variation in intestinal microbial composition. Assessment of pooled results can obscure high individual variation in data. ZnO NPs consumption was not associated with a significant difference in the intestinal microbial community compared to untreated controls. Our results indicated a high individual variation in the intestinal microbiome, which may further point out the importance of functional study over microbial composition to address nanomaterials-microbiome relationship.
See more in PubMed
FEMS Microbiol Lett. 2008 Feb;279(1):71-6 PubMed
Clin Microbiol Rev. 2010 Jan;23(1):35-73 PubMed
Nat Methods. 2010 May;7(5):335-6 PubMed
Proc Natl Acad Sci U S A. 2011 Mar 15;108 Suppl 1:4516-22 PubMed
Appl Environ Microbiol. 2011 Apr;77(7):2325-31 PubMed
Nanotoxicology. 2011 Mar;5(1):79-90 PubMed
Environ Int. 2011 Aug;37(6):1083-97 PubMed
Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):14288-93 PubMed
PLoS One. 2012;7(2):e30440 PubMed
ISME J. 2012 Aug;6(8):1621-4 PubMed
Environ Pollut. 2013 Mar;174:157-63 PubMed
Br J Nutr. 2013 Jan;109 Suppl 2:S21-6 PubMed
Nat Methods. 2013 Oct;10(10):996-8 PubMed
BMC Microbiol. 2013 Nov 09;13:248 PubMed
Microb Ecol. 2015 Jan;69(1):25-36 PubMed
J Adv Res. 2015 May;6(3):283-300 PubMed
Int J Mol Sci. 2016 Apr 06;17(4):509 PubMed
Microbiome. 2016 Aug 12;4(1):44 PubMed
Sci Total Environ. 2017 Feb 1;579:1504-1511 PubMed
Ecotoxicol Environ Saf. 2018 Jan;147:110-116 PubMed
Sci Total Environ. 2018 Feb 1;613-614:62-71 PubMed
Environ Toxicol Chem. 2018 Nov;37(11):2758-2775 PubMed
