Novel nanofibers mats were fabricated by electrospinning of polyvinyl alcohol/hyaluronan (PVA/HA) solutions in the presence of silver nanoparticles (AgNPs). The AgNPs were synthesized by in-situ chemical reduction of silver ions (Ag+) using HA as a reducing and stabilizing agent. Narrow size distribution and spherical shape of AgNPs were achieved by optimizing the initial silver nitrate concentration (0.01 to 1 M) and reaction time (10-60 min). HA-AgNPs nanocomposite and PVA/HA-AgNPs nanofibrous mats were fabricated by electrospinning technique from aqueous solution containing a different mass ratio of PVA and HA-AgNPs and characterized by UV/Vis spectroscopy, SEM, TEM, DLS, XRD, TGA, and ATR-FTIR. Mechanical and rheological properties were also investigated and discussed. The novel nanofibrous mats show great potential in skin regeneration and drug carrier applications.

CEITEC Central European Institute of Technology Brno University of Technology Purkynova 123 Brno 612 00 Brno Czechia

CEITEC Central European Institute of Technology Brno University of Technology Purkynova 123 Brno 612 00 Brno Czechia; Institute of Materials Chemistry Faculty of Chemistry Brno University of Technology Purkynova 118 Brno 612 00 Czechia

CEITEC Central European Institute of Technology Brno University of Technology Purkynova 123 Brno 612 00 Brno Czechia; Pretreatment and Finishing of Cellulosic Fibers Textile Research Division National Research Centre Dokki Cairo Egypt

Department of Physical Electronics Masaryk University Brno Czechia

Institute of Materials Chemistry Faculty of Chemistry Brno University of Technology Purkynova 118 Brno 612 00 Czechia

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Self-Assembled Hydrogel Membranes with Structurally Tunable Mechanical and Biological Properties

Marine Biomaterials: Hyaluronan