INTRODUCTION: At the present time, the skin tumors are among the most common cancers. Optimal therapy is based on the extent of the disease and the age of the patient. The need for radiotherapy occurs for inoperable locally advanced tumors and in the event of failure, salvage surgery is applied. MATERIALS AND METHODS: We provided a case report of an older patient with giant squamous cell skin carcinoma and a review of published articles. RESULTS: We present a rare case of giant squamous cell skin carcinoma with metastatic satellite tumors that was primarily treated with curative radiotherapy. Five months after radiotherapy, a recurrent tumor was detected at the site of origin and the treatment was completed by salvage surgery. Full remission was achieved for four years. CONCLUSION: Despite the seemingly incurable finding it is always necessary to consider radical treatment regardless of the patient´s age. Curative treatment could achieve long term remission in the group of older patients.

1st Faculty of Medicine Charles University 12108 Prague Czech Republic

3rd Faculty of Medicine Charles University 12108 Prague Czech Republic

Department of Clinical and Radiation Oncology Oncology Centre Multiscan and Pardubice Hospital 53002 Pardubice Czech Republic

Department of Otorhinolaryngology Pardubice Hospital 53003 Pardubice Czech Republic

Faculty of Health Studies Pardubice University 53003 Pardubice Czech Republic

Faculty of Medicine and Dentistry Palacky University Olomouc 77147 Olomouc Czech Republic

Faculty of Military Health Sciences University of Defense 50001 Hradec Kralove Czech Republic

Institute for Postgraduate Medical Education 10005 Prague Czech Republic

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