Adipokinetic hormone promotes infection with entomopathogenic fungus Isaria fumosorosea in the cockroach Periplaneta americana
Jazyk angličtina Země Spojené státy americké Médium print-electronic
Typ dokumentu časopisecké články
PubMed
31783176
DOI
10.1016/j.cbpc.2019.108677
PII: S1532-0456(19)30393-X
Knihovny.cz E-zdroje
- Klíčová slova
- AKH expression, Catalase, Insect, Metabolism, Mortality,
- MeSH
- dezinsekce metody MeSH
- hmyzí hormony farmakologie MeSH
- katalasa metabolismus MeSH
- kyselina pyrrolidonkarboxylová analogy a deriváty farmakologie MeSH
- oligopeptidy farmakologie MeSH
- oxid uhličitý metabolismus MeSH
- oxidační stres MeSH
- Periplaneta účinky léků MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- adipokinetic hormone MeSH Prohlížeč
- hmyzí hormony MeSH
- katalasa MeSH
- kyselina pyrrolidonkarboxylová MeSH
- oligopeptidy MeSH
- oxid uhličitý MeSH
The adipokinetic hormones (AKHs) are known to be involved in insect immunity, thus their role in the cockroach Periplaneta americana infected with the entomopathogenic fungus Isaria fumosorosea was examined in this study. The application of I. fumosorosea resulted in a significant increase in both Akh gene expression and AKH peptide levels. Further, co-application of I. fumosorosea with Peram-CAH-II significantly enhanced cockroach mortality compared with the application of I. fumosorosea alone. The mechanism of AKH action could involve metabolic stimulation, which was indicated by a significant increase in carbon dioxide production; this effect can increase the turnover and thus efficacy of toxins produced by I. fumosorosea in the cockroach's body. I. fumosorosea treatment resulted in a significant decrease in haemolymph nutrients (carbohydrates and lipids), but co-application with Peram-CAH-II restored control level of lipids or even further increased the level of carbohydrates. Such nutritional abundance could enhance the growth and development of I. fumosorosea. Further, both I. fumosorosea and Peram-CAH-II probably affected oxidative stress: I. fumosorosea alone curbed the activity of catalase in the cockroach's gut, but co-application with Peram-CAH-II stimulated it. Interestingly, the hormone alone had no effect on catalase activity. Taken together, the results of the present study demonstrate the interactions between the fungus and AKH activity; understanding this relationship could provide insight into AKH action and may have practical implications for insect pest control in the future.
Citace poskytuje Crossref.org
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