Adipokinetic hormone promotes infection with entomopathogenic fungus Isaria fumosorosea in the cockroach Periplaneta americana
Language English Country United States Media print-electronic
Document type Journal Article
PubMed
31783176
DOI
10.1016/j.cbpc.2019.108677
PII: S1532-0456(19)30393-X
Knihovny.cz E-resources
- Keywords
- AKH expression, Catalase, Insect, Metabolism, Mortality,
- MeSH
- Insect Control methods MeSH
- Insect Hormones pharmacology MeSH
- Catalase metabolism MeSH
- Pyrrolidonecarboxylic Acid analogs & derivatives pharmacology MeSH
- Oligopeptides pharmacology MeSH
- Carbon Dioxide metabolism MeSH
- Oxidative Stress MeSH
- Periplaneta drug effects MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- adipokinetic hormone MeSH Browser
- Insect Hormones MeSH
- Catalase MeSH
- Pyrrolidonecarboxylic Acid MeSH
- Oligopeptides MeSH
- Carbon Dioxide MeSH
The adipokinetic hormones (AKHs) are known to be involved in insect immunity, thus their role in the cockroach Periplaneta americana infected with the entomopathogenic fungus Isaria fumosorosea was examined in this study. The application of I. fumosorosea resulted in a significant increase in both Akh gene expression and AKH peptide levels. Further, co-application of I. fumosorosea with Peram-CAH-II significantly enhanced cockroach mortality compared with the application of I. fumosorosea alone. The mechanism of AKH action could involve metabolic stimulation, which was indicated by a significant increase in carbon dioxide production; this effect can increase the turnover and thus efficacy of toxins produced by I. fumosorosea in the cockroach's body. I. fumosorosea treatment resulted in a significant decrease in haemolymph nutrients (carbohydrates and lipids), but co-application with Peram-CAH-II restored control level of lipids or even further increased the level of carbohydrates. Such nutritional abundance could enhance the growth and development of I. fumosorosea. Further, both I. fumosorosea and Peram-CAH-II probably affected oxidative stress: I. fumosorosea alone curbed the activity of catalase in the cockroach's gut, but co-application with Peram-CAH-II stimulated it. Interestingly, the hormone alone had no effect on catalase activity. Taken together, the results of the present study demonstrate the interactions between the fungus and AKH activity; understanding this relationship could provide insight into AKH action and may have practical implications for insect pest control in the future.
References provided by Crossref.org
Insect Body Defence Reactions against Bee Venom: Do Adipokinetic Hormones Play a Role?
