Neuronal Maturation: Challenges and Opportunities in a Nascent Field
Jazyk angličtina Země Anglie, Velká Británie Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem
Grantová podpora
MR/R004463/1
Medical Research Council - United Kingdom
PubMed
32459989
DOI
10.1016/j.tins.2020.02.005
PII: S0166-2236(20)30047-3
Knihovny.cz E-zdroje
- Klíčová slova
- axon growth and regeneration, neural plasticity, neuronal development, neuronal maturation, resilience, synapse,
- MeSH
- dospělí MeSH
- lidé MeSH
- neurogeneze MeSH
- neuroplasticita * MeSH
- regenerace nervu * MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
After its initial development, the nervous system matures to connect and shape the neuronal circuitry and to keep it functional in humans for decades. Here we conceptualize neuronal maturation as a research field that will have, we would argue, a strong impact on understanding the healthy and diseased nervous system. Identifying the key mechanisms underlying neuronal maturation has the potential to reverse this process in adulthood, thereby facilitating regeneration.
Citace poskytuje Crossref.org
Neuronal maturation and axon regeneration: unfixing circuitry to enable repair
