This position statement from the Heart Failure Association of the European Society of Cardiology Cardio-Oncology Study Group in collaboration with the International Cardio-Oncology Society presents practical, easy-to-use and evidence-based risk stratification tools for oncologists, haemato-oncologists and cardiologists to use in their clinical practice to risk stratify oncology patients prior to receiving cancer therapies known to cause heart failure or other serious cardiovascular toxicities. Baseline risk stratification proformas are presented for oncology patients prior to receiving the following cancer therapies: anthracycline chemotherapy, HER2-targeted therapies such as trastuzumab, vascular endothelial growth factor inhibitors, second and third generation multi-targeted kinase inhibitors for chronic myeloid leukaemia targeting BCR-ABL, multiple myeloma therapies (proteasome inhibitors and immunomodulatory drugs), RAF and MEK inhibitors or androgen deprivation therapies. Applying these risk stratification proformas will allow clinicians to stratify cancer patients into low, medium, high and very high risk of cardiovascular complications prior to starting treatment, with the aim of improving personalised approaches to minimise the risk of cardiovascular toxicity from cancer therapies.

1st Department of Medicine Cardioangiology Charles University Prague Medical Faculty and University Hospital Hradec Kralove Prague Czech Republic

Barts Heart Centre and University College London London UK

Breast Unit Royal Marsden Hospital Surrey UK

Cardio Oncology Center of Excellence Washington University in St Louis St Louis MO USA

Cardio Oncology Clinic Heart Failure Unit Attikon University Hospital National and Kapodistrian University of Athens Medical School Athens Greece

Cardio Oncology Department of Cardio Pneumology University of São Paulo São Paulo Brazil

Cardio Oncology Program Brigham and Women's Hospital Harvard Medical School Boston MA USA

Cardio Oncology Program Department of Medicine Vanderbilt University Medical Center Nashville TN USA

Cardio Oncology Program Division of Cardiology Department of Medicine Massachusetts General Hospital Harvard Medical School Boston MA USA

Cardio Oncology Service Royal Brompton Hospital and Imperial College London UK

Cardiology Division Internal Medicine Department American University of Beirut Medical Center Beirut Lebanon

Cardiology Service Cardio Oncology Unit La Paz University Hospital and IdiPAz Research Institute Ciber CV Madrid Spain

Cardioncology Unit European Institute of Oncology IRCCS Milan Italy

Comprehensive Heart Failure Center University Clinic Würzburg Würzburg Germany

Department of Cardiology and Angiology Hannover Medical School Hannover Germany

Department of Cardiology and Pneumology University of Goettingen Medical Center Goettingen Germany

Department of Cardiology Bern University Hospital Inselspital University of Bern Bern Switzerland

Department of Cardiology Medical University of Vienna Vienna Austria

Department of Cardiology National University Heart Centre Singapore National University Health System Singapore Singapore

Department of Cardiology The Newcastle upon Tyne Hospitals NHS Foundation Trust and Newcastle University Newcastle UK

Department of Cardiology University of Groningen University Medical Center Groningen Groningen The Netherlands

Department of Cardiovascular Diseases Mayo Clinic Rochester MN USA

Department of Clinical Oncology Royal Marsden Hospital and Institute of Cancer Research London UK

Department of Community Cardiology Tel Aviv Jaffa District Clalit Health Fund and Sackler Faculty of Medicine Tel Aviv University Tel Aviv Israel

Department of Haematological Medicine King's College Hospital London UK

Department of Haematology Hammersmith Hospital Imperial College London UK

Department of Medical Imaging and Radiation Sciences Monash University and Department of Medicine Melbourne University Melbourne Australia

Department of Oncology University of Cambridge and NIHR Cambridge Biomedical Research Centre Cambridge UK

Department of Precision Medicine Luigi Vanvitelli University of Campania Naples Italy

Department of Translational Medical Sciences and Interdepartmental Center for Clinical and Translational Research Federico 2 University Naples Italy

Division of Cardiology and Metabolism Department of Cardiology Charité and Berlin Institute of Health Center for Regenerative Therapies partner site Berlin and Department of Cardiology Charité Campus Benjamin Franklin Berlin Germany

Division of Medical Oncology Sinai Health System Mount Sinai Hospital Toronto Canada

Duke Cancer Institute Duke University Durham NC USA

Emergency Institute for Cardiovascular Diseases 'Prof C C Iliescu' Bucharest Romania

Faculty of Medicine and Serbian Academy of Sciences and Arts University of Belgrade Belgrade Serbia

German Center for Cardiovascular Research partner site Goettingen Goettingen Germany

Institute of Molecular and Translational Therapeutic Strategies Hannover Medical School Hannover Germany

Liverpool Centre for Cardiovascular Science Liverpool Heart and Chest Hospital Liverpool UK

MedStar Heart and Vascular Institute Georgetown University Washington DC USA

Memorial Sloan Kettering Cancer Center New York NY USA

National Amyloidosis Centre University College London London UK

Pharmacology Centre of Clinical and Experimental Medicine IRCCS San Raffaele Pisana Rome Italy

Santa Cardio Oncology Santa Casa de São Paulo and Rede Dor São Luiz São Paulo Brazil

School of Medicine and Public Health University of Newcastle and Cancer and the Heart Program Hunter New England LHD Newcastle Australia

Sechenov Medical University Moscow Russia

Stanford University School of Medicine Stanford CA USA

Ted Rogers Program in Cardiotoxicity Prevention and Joint Division of Medical Imaging Peter Munk Cardiac Center Toronto General Hospital University Health Network University of Toronto Toronto Canada

UMR S 942 Paris University Cardiology Department Lariboisiere Hospital AP HP Paris France

University Heart Center Department of Cardiology University Hospital Zurich Zurich Switzerland

University of Cyprus Medical School Nicosia Cyprus

University of Medicine Carol Davila Bucharest Romania

University of Pennsylvania Philadelphia PA USA

University of Warwick Warwick UK

Vanderbilt University Medical Center Nashville TN USA

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The Digital Revolution in Medicine: Applications in Cardio-Oncology

European Society of Cardiology quality indicators for the prevention and management of cancer therapy-related cardiovascular toxicity in cancer treatment