Impact of COVID-19 Pandemic on Mechanical Reperfusion for Patients With STEMI
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu časopisecké články, multicentrická studie
PubMed
33183506
PubMed Central
PMC7834750
DOI
10.1016/j.jacc.2020.09.546
PII: S0735-1097(20)37239-9
Knihovny.cz E-zdroje
- Klíčová slova
- COVID-19, STEMI, primary angioplasty,
- MeSH
- COVID-19 MeSH
- infarkt myokardu s elevacemi ST úseků mortalita terapie MeSH
- koronární angioplastika statistika a číselné údaje MeSH
- koronavirové infekce * MeSH
- lidé středního věku MeSH
- lidé MeSH
- pandemie * MeSH
- registrace * MeSH
- retrospektivní studie MeSH
- senioři MeSH
- virová pneumonie * MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- multicentrická studie MeSH
- Geografické názvy
- Evropa epidemiologie MeSH
BACKGROUND: The fear of contagion during the coronavirus disease-2019 (COVID-19) pandemic may have potentially refrained patients with ST-segment elevation myocardial infarction (STEMI) from accessing the emergency system, with subsequent impact on mortality. OBJECTIVES: The ISACS-STEMI COVID-19 registry aims to estimate the true impact of the COVID-19 pandemic on the treatment and outcome of patients with STEMI treated by primary percutaneous coronary intervention (PPCI), with identification of "at-risk" patient cohorts for failure to present or delays to treatment. METHODS: This retrospective registry was performed in European high-volume PPCI centers and assessed patients with STEMI treated with PPPCI in March/April 2019 and 2020. Main outcomes are the incidences of PPCI, delayed treatment, and in-hospital mortality. RESULTS: A total of 6,609 patients underwent PPCI in 77 centers, located in 18 countries. In 2020, during the pandemic, there was a significant reduction in PPCI as compared with 2019 (incidence rate ratio: 0.811; 95% confidence interval: 0.78 to 0.84; p < 0.0001). The heterogeneity among centers was not related to the incidence of death due to COVID-19. A significant interaction was observed for patients with arterial hypertension, who were less frequently admitted in 2020 than in 2019. Furthermore, the pandemic was associated with a significant increase in door-to-balloon and total ischemia times, which may have contributed to the higher mortality during the pandemic. CONCLUSIONS: The COVID-19 pandemic had significant impact on the treatment of patients with STEMI, with a 19% reduction in PPCI procedures, especially among patients suffering from hypertension, and a longer delay to treatment, which may have contributed to the increased mortality during the pandemic. (Primary Angioplasty for STEMI During COVID-19 Pandemic [ISACS-STEMI COVID-19] Registry; NCT04412655).
AUSL IRCCS Reggio Emilia Italy
Azienda Ospedaliero Universitaria Ospedali Riuniti Trieste Italy
Azienda Ospedaliero Universitaria Sassari Sassari Italy
Center for Cardiovascular Diseases Ohrid North Macedonia
Center Hospitalier Universitaire de Poitiers Poitiers University Hospital Poitiers France
Central Hospital of Medical University of Lodz Lodz Poland
Centre for Intensive Internal Medicine University Medical Centre Ljubljana Slovenia
Charles University Hospital Prague Czech Republic
Clinic Emergency Hospital of Bucharest Bucharest Romania
Complexo Hospetaliero Universitario La Coruna La Coruna Spain
Department of Cardiology Medisch Spectrum Twente Thoraxcentrum Twente Enschede the Netherlands
Department of Statistical Sciences University of Padova Padova Italy
Division of Cardiology Amphia Hospital Breda the Netherlands
Division of Cardiology Attikon University Hospital Athens Greece
Division of Cardiology Azienda Ospedaliera Ospedali Riuniti Marche Nord Pesaro Italy
Division of Cardiology CHU Lariboisière AP HP Paris 7 University INSERM UMRS 942 Paris France
Division of Cardiology CHU Timone Aix Marseille Université Marseille France
Division of Cardiology Clinica Villa dei Fiori Acerra Italy
Division of Cardiology Complejo Hospitalario de Toledo Toledo Spain
Division of Cardiology Groupe Hospitalier Mutualiste de Grenoble Grenoble France
Division of Cardiology Heart Centre Turku University Hospital Turku Finland
Division of Cardiology Helsinki University Central Hospital Helsinki Finland
Division of Cardiology Hospital Cabueñes Gijon Spain
Division of Cardiology Hospital Clinico Universitario de Valencia Spain
Division of Cardiology Hospital de Santa Cruz CHLO Carnaxide Lisbon Portugal
Division of Cardiology Hospital la Paz Madrid Spain
Division of Cardiology Hospital Puerta de Hierro Majadahonda Spain
Division of Cardiology Hospital Puerta del Mar Cadiz Spain
Division of Cardiology Hospital Universitario de Canarias Santa Cruz de Tenerife Spain
Division of Cardiology Jessa Ziekenhuis Hasselt Belgium
Division of Cardiology Juan Ramon Jimenez Hospital Huelva Spain
Division of Cardiology Maasstad Ziekenhuis Rotterdam the Netherlands
Division of Cardiology Medical University of Silezia Katowice Poland
Division of Cardiology Northwest Clinics Alkmaar the Netherlands
Division of Cardiology Odense Universitets Hospital Odense Denmark
Division of Cardiology Ospedale A Manzoni Lecco Italy
Division of Cardiology Ospedale Civico Arnas Palermo Italy
Division of Cardiology Ospedale degli Infermi ASL Biella Biella Italy
Division of Cardiology Ospedale del Mare Napoli Italy
Division of Cardiology Ospedale F Spaziani Frosinone Italy
Division of Cardiology Ospedale G Moscati Aversa Italy
Division of Cardiology Ospedale Maggiore Bologna Italy
Division of Cardiology Ospedale S Maurizio Bolzano Ospedale S Maurizio Bolzano Italy
Division of Cardiology Ospedale San Giovanni di Dio e Ruggi d'Aragona Salerno Italy
Division of Cardiology Ospedale Sant'Anna Ferrara Italy
Division of Cardiology Ospedale Santa Maria della Misericordia Udine Italy
Division of Cardiology Ospedale Santa Maria delle Grazie Pozzuoli Italy
Division of Cardiology Ospedale Santa Maria Goretti Latina Italy
Division of Cardiology Ospedali Riuniti Reggio Calabria Italy
Division of Cardiology Oulu University Hospital Oulu Finland
Division of Cardiology St Antonius Hospital Nieuwegein the Netherlands
Division of Cardiology St Jan Hospital Brugge Belgium
Division of Cardiology UMC Utrecht the Netherlands
Division of Cardiology University Hospital Dijon France
Division of Cardiology University Hospital of Wales Cardiff United Kingdom
Division of Cardiology Ziekenhuis Netwerk Antwerpen Middelheim Antwerp Belgium
H Universitario y Politécnico La Fe Valencia Spain
Hospital Clínico Universitario Virgen de la Victoria Málaga Spain
Hospital Germans Triasi Pujol Badalona Spain
Institute of Cardiology Jagiellonian University Medical College Krakow Poland
Interventional Cardiology Unit Azienda Ospedaliera Sanitaria Parma Italy
Interventional Cardiology Unit Azienda Ospedaliero Universitaria Ospedali Riuniti Ancona Italy
Invasive Cardiology and Congenital Heart Disease Patras University Hospital Patras Greece
John Radcliffe Hospital Oxford United Kingdom
Mastricht University Medical Center Maastricht the Netherlands
Onze Lieve Vrouwe Gasthuis Amsterdam the Netherlands
Ospedale Santa Chiara Trento Italy
Ospedale Santa Maria della Misericordia Perugia Italy
University Hospital Birmingham Birmingham United Kingdom
University Hospital Brno Medical Faculty of Masaryk University Brno Czech Republic
University Hospital Munich Ludwig Maximilians University Munich Germany
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ClinicalTrials.gov
NCT04412655