A novel postgraduate endoscopic course using a large animal model of secondary Crohn's disease stricture
Jazyk angličtina Země Německo Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
33661380
DOI
10.1007/s00464-021-08360-x
PII: 10.1007/s00464-021-08360-x
Knihovny.cz E-zdroje
- Klíčová slova
- Animal model, Crohn’s disease, Inflammatory bowel disease, Interventional endoscopy, Stricturotomy, Training,
- MeSH
- Crohnova nemoc * komplikace chirurgie MeSH
- dilatace MeSH
- lidé MeSH
- modely nemocí na zvířatech MeSH
- prasata MeSH
- stenóza etiologie chirurgie MeSH
- výsledek terapie MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
BACKGROUND: The increasing complexity of advanced endoscopic techniques places a high demand on the endoscopist's expertise. Thus, live porcine models have been more frequently used for training. We briefly describe a hands-on postgraduate endoscopic course regarding a novel method of treatment of anastomotic strictures in a porcine model. METHODS: The porcine model of Crohn's disease anastomotic stricture with two artificial side-to-side ileo-colonic anastomoses was used. Participants performed endoscopic stricturotomy under supervision at one of two equipped endoscopic stations. Available animals were endoscopically re-examined 3 months after the course. RESULTS: Twelve anastomoses were prepared for the course. Eleven circumferential stricturotomies together with horizontal cut and clip placement were conducted. All anastomoses were passable for the scope after the procedure, and no case of perforation or bleeding occurred. All anastomoses available for re-examination remained passable for the endoscope after 3 months. CONCLUSION: We successfully organised the first endoscopic hands-on course for the training of endoscopic stricturotomy on a large animal model.
IBD Clinical and Research Center ISCARE a s Ceskomoravska 2510 19 Prague 9 190 00 Czech Republic
Institute of Pharmacology 1st Faculty of Medicine Charles University Prague Czech Republic
Royal Lancaster Infirmary University Hospitals of Morecambe Bay NHS Foundation Trust Lancaster UK
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