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Cecchi I, Arias de la Rosa I, Menegatti E, Roccatello D, Collantes-Estevez E, Lopez-Pedrera C. Neutrophils: Novel key players in rheumatoid arthritis. Current and future therapeutic targets. Autoimmun. Rev. 2018;17:1138–1149. doi: 10.1016/j.autrev.2018.06.006.
PubMed
DOI
Cross A, Bakstad D, Allen JC, Thomas L, Moots RJ, Edwards SW. Neutrophil gene expression in rheumatoid arthritis. Pathophysiol. Off. J. Int. Soc. Pathophysiol. 2005;12:191–202.
PubMed
Mayadas TN, Cullere X, Lowell CA. The multifaceted functions of neutrophils. Annu. Rev. Pathol. Mech. Dis. 2014;9:181–218. doi: 10.1146/annurev-pathol-020712-164023.
PubMed
DOI
PMC
Steinberg BE, Grinstein S. Unconventional roles of the NADPH oxidase: Signaling, ion homeostasis, and cell death. Sci. STKE. 2007;20:7.
PubMed
Brinkmann V, Reichard U, Goosmann C, Fauler B, Uhlemann Y, Weiss DS, et al. Neutrophil extracellular traps kill bacteria. Science. 2004;303:1532–1535. doi: 10.1126/science.1092385.
PubMed
DOI
Mitroulis I, Kambas K, Chrysanthopoulou A, Skendros P, Apostolidou E, Kourtzelis I, et al. Neutrophil extracellular trap formation is associated with IL-1b and autophagy-related signaling in Gout. PLoS ONE. 2011;6:2. doi: 10.1371/journal.pone.0029318.
PubMed
DOI
PMC
Lin AM, Rubin CJ, Khandpur R, Wang JY, Riblett M, Yalavarthi S, et al. Mast cells and neutrophils release IL-17 through extracellular trap formation in psoriasis. J. Immunol. 2011;187:490–500. doi: 10.4049/jimmunol.1100123.
PubMed
DOI
PMC
Villanueva E, Yalavarthi S, Berthier CC, Hodgin JB, Khandpur R, Lin AM, et al. Netting neutrophils induce endothelial damage, infiltrate tissues, and expose immunostimulatory molecules in systemic lupus erythematosus. J. Immunol. 2011;187:538–552. doi: 10.4049/jimmunol.1100450.
PubMed
DOI
PMC
Khandpur R, Carmona-Rivera C, Vivekanandan-Giri A, Yalavarthi S, Knight JS, Friday S, et al. NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis. Sci. Transl. Med. 2014;5:178.
PubMed
PMC
Magna M, Pisetsky DS. The alarmin properties of DNA and DNA-associated nuclear proteins. Clin. Ther. 2016;38:1029–1041. doi: 10.1016/j.clinthera.2016.02.029.
PubMed
DOI
Denning NL, Aziz M, Gurien SD, Wang P. Damps and nets in sepsis. Front. Immunol. 2019;10:1–15. doi: 10.3389/fimmu.2019.02536.
PubMed
DOI
PMC
Tadie JM, Bae HB, Jiang S, Park DW, Bell CP, Yang H, et al. HMGB1 promotes neutrophil extracellular trap formation through interactions with Toll-like receptor 4. Am. J. Physiol. Lung Cell. Mol. Physiol. 2013;304:8–12. doi: 10.1152/ajplung.00151.2012.
PubMed
DOI
PMC
Donato R, Cannon B, Sorci G, Riuzzi F, Hsu K, Weber J, et al. Functions of S100 proteins. Curr. Mol. Med. 2012;13:24–57. doi: 10.2174/1566524011307010024.
PubMed
DOI
PMC
Foell D, Wittkowski H, Vogl T, Roth J. S100 proteins expressed in phagocytes: A novel group of damage-associated molecular pattern molecules. J. Leuk. Biol. 2007;81:28–37. doi: 10.1189/jlb.0306170.
PubMed
DOI
Andrés Cerezo L, Remáková M, Tomčik M, Gay S, Neidhart M, Lukanidin E, et al. The metastasis-associated protein S100A4 promotes the inflammatory response of mononuclear cells via the TLR4 signalling pathway in rheumatoid arthritis. Rheumatol. 2014;53:1520–1526. doi: 10.1093/rheumatology/keu031.
PubMed
DOI
Andrés Cerezo L, Šumová B, Prajzlerová K, Veigl D, Damgaard D, Nielsen CH, et al. Calgizzarin (S100A11): A novel inflammatory mediator associated with disease activity of rheumatoid arthritis. Arthritis Res. Ther. 2017;19:1–10. doi: 10.1186/s13075-017-1288-y.
PubMed
DOI
PMC
Yammani RR. S100 proteins in cartilage: Role in arthritis. Biochim. Biophys. Acta - Mol. Basis Dis. 2012;1822:600–606. doi: 10.1016/j.bbadis.2012.01.006.
PubMed
DOI
PMC
Gravius S, Randau TM, Casadonte R, Kriegsmann M, Friedrich MJ, Kriegsmann J. Investigation of neutrophilic peptides in periprosthetic tissue by matrix-assisted laser desorption ionisation time-of-flight imaging mass spectrometry. Int. Orthop. 2015;39:559–567. doi: 10.1007/s00264-014-2544-2.
PubMed
DOI
Schenten V, Plançon S, Jung N, Hann J, Bueb J. Secretion of the phosphorylated form of S100A9 from neutrophils is essential for the proinflammatory functions of extracellular S100A8/A9. Front. Immunol. 2018;9:2. doi: 10.3389/fimmu.2018.00447.
PubMed
DOI
PMC
Urban CF, Ermert D, Schmid M, Abu-Abed U, Goosmann C, Nacken W, et al. Neutrophil extracellular traps contain calprotectin, a cytosolic protein complex involved in host defense against Candida albicans. Plos Patghens. 2009;5(e1000639):1–18.
PubMed
PMC
Pieterse E, Rother N, Yanginlar C, Hilbrands LB, van der Vlag J. Neutrophils discriminate between lipopolysaccharides of different bacterial sources and selectively release neutrophil extracellular traps. Front. Immunol. 2016;7:1–13. doi: 10.3389/fimmu.2016.00484.
PubMed
DOI
PMC
Mitsui Y, Tomonobu N, Watanabe M, Kinoshita R, Wayan Sumardika I, Youyi C, et al. Upregulation of mobility in pancreatic cancer cells by secreted S100A11 through activation of surrounding fibroblasts. Oncol. Res. 2019;27:945–956. doi: 10.3727/096504019X15555408784978.
PubMed
DOI
PMC
Zhang S, Wang Z, Liu W, Lei R, Shan J, Li L. Distinct prognostic values of S100 mRNA expression in breast cancer. Nat. Sci. Rep. 2017;7:1–11. doi: 10.1038/s41598-016-0028-x.
PubMed
DOI
PMC
Ji Y, Huang HUA, Jiang F, Ni R, Xiao M. S100 family signaling network and related proteins in pancreatic cancer (review ) Int. J. Mol. Med. 2014;33:769–776. doi: 10.3892/ijmm.2014.1633.
PubMed
DOI
Takamatsu H, Yamamoto K, Tomonobu N, Murata H, Inoue Y, Yamauchi A, et al. Extracellular S100A11 plays a critical role in spread of the fibroblast population in pancreatic cancers. Oncol. Res. 2019;27:713–727. doi: 10.3727/096504018X15433161908259.
PubMed
DOI
PMC
Andrés Cerezo L, Šumová B, Prajzlerová K, Veigl D, Damgaard D, Nielsen CH, et al. S100A11 (calgizzarin) is released by circulating mononuclear cells and its elevated plasma levels distinguish systemic lupus erythematosus patients from healthy individuals. Clin. Exp. Rheumatol. 2019;11:338–339.
PubMed
Andrés Cerezo L, Hulejová H, Šumová B, Kropáčková T, Kryštůfková O, Klein M, et al. Cytokine Pro-in fl ammatory S100A11 is elevated in in fl ammatory myopathies and re fl ects disease activity and extramuscular manifestations in myositis. Cytokine. 2019;116:13–20. doi: 10.1016/j.cyto.2018.12.023.
PubMed
DOI
Tardif MR, Chapeton-Montes JA, Posvandzic A, Pagé N, Gilbert C, Tessier PA. Secretion of S100A8, S100A9, and S100A12 by neutrophils involves reactive oxygen species and potassium efflux. J. Immunol. Res. 2015;2015:296149. doi: 10.1155/2015/296149.
PubMed
DOI
PMC
Boye K, Mælandsmo GM. S100A4 and metastasis: A small actor playing many roles. Am. J. Pathol. 2010;176:528–535. doi: 10.2353/ajpath.2010.090526.
PubMed
DOI
PMC
Cross A, Bucknall RC, Cassatella MA, Edwards SW, Moots RJ. Synovial fluid neutrophils transcribe and express class II major histocompatibility complex molecules in rheumatoid arthritis. Arthritis Rheum. 2003;48:2796–2806. doi: 10.1002/art.11253.
PubMed
DOI
de Bont CM, Koopman WJH, Boelens WC, Pruijn GJM. Stimulus-dependent chromatin dynamics, citrullination, calcium signalling and ROS production during NET formation. Biochim. Biophys. Acta Mol. Cell Res. 2018;1865:1621–1629. doi: 10.1016/j.bbamcr.2018.08.014.
PubMed
DOI
Cecil DL, Johnson K, Rediske J, Schmidt AM, Terkeltaub R. Inflammation-induced chondrocyte hypertrophy is driven by receptor for advanced glycation end products. J. Immunol. 2005;175:8296–8302. doi: 10.4049/jimmunol.175.12.8296.
PubMed
DOI
Holzinger D, Nippe N, Vogl T, Marketon K, Mysore V, Weinhage T, et al. Myeloid-related proteins 8 and 14 contribute to monosodium urate monohydrate crystal-induced inflammation in gout. Arthritis Rheum. 2014;66:1327–1339. doi: 10.1002/art.38369.
PubMed
DOI
Chowdhury ChS, Giaglis S, Walker UA, Buser A, Hahn S, Hasler P. Enhanced neutrophil extracellular trap generation in rheumatoid arthritis: Analysis of underlying signal transduction pathways and potential diagnostic utility. Arthritis Res. Ther. 2014;16:R122. doi: 10.1186/ar4579.
PubMed
DOI
PMC
Weinmann P, Moura RA, Caetano-Lopes JR, Pereira PA, Canhão H, Queiroz MV, et al. Delayed neutrophil apoptosis in very early rheumatoid arthritis patients is abrogated by methotrexate therapy”. Clin. Exp. Rheumatol. 2007;25(6):885–887.
PubMed
de Siqueira MB, da Mota LM, Couto SC, Muniz-Junqueira MI. Enhanced neutrophil phagocytic capacity in rheumatoid arthritis related to the autoantibodies rheumatoid factor and anti-cyclic citrullinated peptides. BMC Musculoskelet. Disord. 2015;16:159. doi: 10.1186/s12891-015-0616-0.
PubMed
DOI
PMC
Naegelen I, Beaume N, Plançon S, Schenten V, Tschirhart EJ, Bréchard S. Regulation of neutrophil degranulation and cytokine secretion: A novel model approach based on linear fitting. J. Immunol. Res. 2015;2015:817038. doi: 10.1155/2015/817038.
PubMed
DOI
PMC
Dempsey AC, Walsh MP, Shaw GS. Unmasking the annexin I interaction from the structure of Apo-S100A11. Structure. 2003;11:887–897. doi: 10.1016/S0969-2126(03)00126-6.
PubMed
DOI
Takahashi T, Mamada A, Kizawa K, Suzuki R. Age-dependent damage of hair cuticle: Contribution of S100A3 protein and its citrullination. J. Cosmet. Dermatol. 2016;15:211–218. doi: 10.1111/jocd.12202.
PubMed
DOI
Oslejsková L, Grigorian M, Hulejová H, Vencovský J, Pavelka K, Klingelhofer J, et al. Metastasis-inducing S100A4 protein is associated with the disease activity of rheumatoid arthritis. Rheumatology (Oxford) 2009;48:1590–1594. doi: 10.1093/rheumatology/kep316.
PubMed
DOI
Arnett FC, Edworthy SM, Bloch DA, Mcshane DJ, Fries JF, Cooper NS, et al. The american rheumatism associaction 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 1987;31:315–324. doi: 10.1002/art.1780310302.
PubMed
DOI
Damgaard D, Senolt L, Nielsen MF, Pruijn GJ, Nielsen CH. Demonstration of extracellular peptidylarginine deiminase (PAD) activity in synovial fluid of patients with rheumatoid arthritis using a novel assay for citrullination of fibrinogen. Arthritis Res. Ther. 2014;16:498. doi: 10.1186/s13075-014-0498-9.
PubMed
DOI
PMC