TNF-alfa [Tumor Necrosis Factor-alpha] tematický
- Termíny
-
kachektin
TNF-α
tumor nekrotizující faktor alfa
-
Cachectin
Cachectin-Tumor Necrosis Factor
TNF Superfamily, Member 2
TNF-alpha
TNFalpha
Tumor Necrosis Factor
Tumor Necrosis Factor Ligand Superfamily Member 2
Perzistentní odkaz
https://www.medvik.cz/link/D014409
Definice
Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.
Povolená podhesla
- AG
- agonisté 2
- AN
- analýza 27
- AI
- antagonisté a inhibitory 748
- AD
- aplikace a dávkování 151
- BI
- biosyntéza 31
- CS
- chemická syntéza 0
- CH
- chemie 4
- HI
- dějiny 1
- EC
- ekonomika 11
- PK
- farmakokinetika 61
- PD
- farmakologie 89
- PH
- fyziologie 18
- GE
- genetika 71
- IM
- imunologie 69
- IP
- izolace a purifikace 14
- CL
- klasifikace 7
- BL
- krev 70
- ME
- metabolismus 109
- UR
- moč 1
- CF
- mozkomíšní mok 0
- DF
- nedostatek 1
- ST
- normy 0
- PO
- otrava 0
- AE
- škodlivé účinky 137
- TU
- terapeutické užití 345
- TO
- toxicita 2
- DE
- účinky léků 46
- RE
- účinky záření 1
- UL
- ultrastruktura 0
- SD
- zásobování a distribuce 0
123
Výskyt v záznamech Medvik
D
Chemikálie a léčiva
D09
sacharidy
D09.400 glykokonjugáty
D09.400.430 glykoproteiny
D09.400.430.250 aktiviny
D09.400.430.500 proteiny ADAM
D09.400.430.563 alfa-1-antichymotrypsin
D09.400.430.594 alfa-1-antitrypsin
D09.400.430.610 alfa-2-antiplasmin
D09.400.430.618 fetuin A
D09.400.430.625 antimülleriánský hormon
D09.400.430.657 asialoglykoproteiny
D09.400.430.673 avidin
D09.400.430.681 faktor aktivující B-buňky
D09.400.430.685 ligand 4-1BB
D09.400.430.687 beta-2-glykoprotein I
D09.400.430.688 antigeny CD70
D09.400.430.700 transportní proteiny pro estery cholesterolu
D09.400.430.750 klusterin
D09.400.430.775 faktory stimulující kolonie
D09.400.430.780 inhibiční protein komplementu C1
D09.400.430.800 fibriliny
D09.400.430.825 glykované proteiny
D09.400.430.850 glykodelin
D09.400.430.860 hemopexin
D09.400.430.870 proteiny tepelného šoku HSP47
D09.400.430.883 inhibiny
D09.400.430.887 laktoferrin
D09.400.430.890 membránové glykoproteiny
D09.400.430.900 mukoproteiny
D09.400.430.910 myelinový P0 protein
D09.400.430.912 osteonektin
D09.400.430.915 protein C
D09.400.430.920 protein S
D09.400.430.930 proteoglykany
D09.400.430.940 sérový amyloidový protein
D09.400.430.950 sialoglykoproteiny
D09.400.430.952 thyreoglobulin
D09.400.430.955 proteiny vázající thyroxin
D09.400.430.960 transkortin
D09.400.430.965 TNF-alfa
D09.400.430.982 vitronektin
D09.400.430.998 Zn-alfa-2-glykoprotein
D12 aminokyseliny, peptidy a proteiny
D12.644 peptidy
D12.644.276 mezibuněčné signální peptidy a proteiny
D12.644.276.374 cytokiny
D12.644.276.374.500 monokiny
D12.644.276.374.500.400 interleukin-1
D12.644.276.374.500.800 TNF-alfa
D12.644.276.374.750 tumor nekrotizující faktory
D12.644.276.374.750.030 antigeny CD70
D12.644.276.374.750.061 faktor aktivující B-buňky
D12.644.276.374.750.065 ligand 4-1BB
D12.644.276.374.750.092 ligand CD30
D12.644.276.374.750.124 ligand CD40
D12.644.276.374.750.155 cytokin TWEAK
D12.644.276.374.750.186 ektodysplasiny
D12.644.276.374.750.249 ligand Fas
D12.644.276.374.750.500 lymfotoxin-alfa
D12.644.276.374.750.505 lymfotoxin-alfa1, beta2-heterotrimer
D12.644.276.374.750.515 lymfotoxin-beta
D12.644.276.374.750.531 ligand OX40
D12.644.276.374.750.562 ligand RANK
D12.644.276.374.750.625 protein TRAIL
D12.644.276.374.750.626 TNF-alfa
D12.644.276.374.750.656 protein TALL-2
D12.644.276.374.750.690 protein TNFSF14
D12.644.276.374.750.720 ligand TL1
D12.776 proteiny
D12.776.124 krevní proteiny
D12.776.124.050 proteiny akutní fáze
D12.776.124.117 beta-2-glykoprotein I
D12.776.124.125 koagulační faktory
D12.776.124.197 transportní proteiny pro estery cholesterolu
D12.776.124.270 fibrin
D12.776.124.335 glykované sérové proteiny
D12.776.124.400 hemoglobiny
D12.776.124.486 imunoproteiny
D12.776.124.625 destičkový růstový faktor
D12.776.124.650 protein C
D12.776.124.670 protein S
D12.776.124.698 plazmatické proteiny vázající retinol
D12.776.124.727 sérový albumin
D12.776.124.790 sérové globuliny
D12.776.124.862 somatomediny
D12.776.124.885 proteiny vázající thyroxin
D12.776.124.900 TNF-alfa
D12.776.124.920 vitronektin
D12.776.395 glykoproteiny
D12.776.395.022 aktiviny
D12.776.395.033 proteiny ADAM
D12.776.395.045 alfa-1-antichymotrypsin
D12.776.395.068 alfa-1-antitrypsin
D12.776.395.080 alfa-2-antiplasmin
D12.776.395.086 fetuin A
D12.776.395.089 antimülleriánský hormon
D12.776.395.092 antigeny CD70
D12.776.395.140 asialoglykoproteiny
D12.776.395.175 avidin
D12.776.395.191 faktor aktivující B-buňky
D12.776.395.192 ligand 4-1BB
D12.776.395.195 beta-2-glykoprotein I
D12.776.395.199 transportní proteiny pro estery cholesterolu
D12.776.395.207 klusterin
D12.776.395.240 faktory stimulující kolonie
D12.776.395.320 inhibiční protein komplementu C1
D12.776.395.341 fibriliny
D12.776.395.351 glykované proteiny
D12.776.395.361 glykodelin
D12.776.395.401 hemopexin
D12.776.395.420 proteiny tepelného šoku HSP47
D12.776.395.439 inhibiny
D12.776.395.507 laktoferrin
D12.776.395.550 membránové glykoproteiny
D12.776.395.560 mukoproteiny
D12.776.395.570 myelinový P0 protein
D12.776.395.600 osteonektin
D12.776.395.635 protein C
D12.776.395.642 protein S
D12.776.395.650 proteoglykany
D12.776.395.690 sérový amyloidový protein
D12.776.395.700 sialoglykoproteiny
D12.776.395.768 thyreoglobulin
D12.776.395.832 proteiny vázající thyroxin
D12.776.395.901 transkortin
D12.776.395.930 TNF-alfa
D12.776.395.970 vitronektin
D12.776.395.985 Zn-alfa-2-glykoprotein
D12.776.467 mezibuněčné signální peptidy a proteiny
D12.776.467.374 cytokiny
D12.776.467.374.500 monokiny
D12.776.467.374.500.400 interleukin-1
D12.776.467.374.500.800 TNF-alfa
D12.776.467.374.750 tumor nekrotizující faktory
D12.776.467.374.750.030 antigeny CD70
D12.776.467.374.750.061 faktor aktivující B-buňky
D12.776.467.374.750.065 ligand 4-1BB
D12.776.467.374.750.092 ligand CD30
D12.776.467.374.750.124 ligand CD40
D12.776.467.374.750.155 cytokin TWEAK
D12.776.467.374.750.186 ektodysplasiny
D12.776.467.374.750.249 ligand Fas
D12.776.467.374.750.500 lymfotoxin-alfa
D12.776.467.374.750.505 lymfotoxin-alfa1, beta2-heterotrimer
D12.776.467.374.750.515 lymfotoxin-beta
D12.776.467.374.750.531 ligand OX40
D12.776.467.374.750.562 ligand RANK
D12.776.467.374.750.625 protein TRAIL
D12.776.467.374.750.626 TNF-alfa
D12.776.467.374.750.656 protein TALL-2
D12.776.467.374.750.690 protein TNFSF14
D12.776.467.374.750.710 ligand TL1
D23 biologické faktory
D23.529 mezibuněčné signální peptidy a proteiny
D23.529.374 cytokiny
D23.529.374.500 monokiny
D23.529.374.500.400 interleukin-1
D23.529.374.500.800 TNF-alfa
D23.529.374.750 tumor nekrotizující faktory
D23.529.374.750.030 antigeny CD70
D23.529.374.750.061 faktor aktivující B-buňky
D23.529.374.750.065 ligand 4-1BB
D23.529.374.750.092 ligand CD30
D23.529.374.750.124 ligand CD40
D23.529.374.750.155 cytokin TWEAK
D23.529.374.750.186 ektodysplasiny
D23.529.374.750.249 ligand Fas
D23.529.374.750.500 lymfotoxin-alfa
D23.529.374.750.505 lymfotoxin-alfa1, beta2-heterotrimer
D23.529.374.750.515 lymfotoxin-beta
D23.529.374.750.531 ligand OX40
D23.529.374.750.562 ligand RANK
D23.529.374.750.625 protein TRAIL
D23.529.374.750.626 TNF-alfa
D23.529.374.750.656 protein TALL-2
D23.529.374.750.690 protein TNFSF14
D23.529.374.750.710 ligand TL1