cytokin TWEAK [Cytokine TWEAK]

tematický
2
Termíny

slabý induktor apoptózy skupiny tumor nekrotizujícího faktoru
slabý induktor apoptózy TNF
TNF příbuzný slabý induktor apoptózy
TWEAK

 

Apo3 Ligand
TNF-Related Weak Inducer of Apoptosis
Tumor Necrosis Factor Ligand Superfamily Member 12
TWEAK Cytokine

Perzistentní odkaz   https://www.medvik.cz/link/D000074049
Definice

A proteolytically-cleaved membrane glycoprotein and member of the TNF superfamily that is highly expressed in a variety of tissues including heart, pancreas, brain, and peripheral blood lymphocytes. The secreted extracellular form is a weak inducer of APOPTOSIS for some cell types and a ligand for the FN14 RECEPTOR. It mediates activation of NF-KAPPA-B and promotes ANGIOGENESIS and proliferation of ENDOTHELIAL CELLS, as well as expression of cytokines involved in INFLAMMATION.

DUI
D000074049 MeSH Prohlížeč
CUI
M000625319
Předchozí užití
Tumor Necrosis Factors (2006-2017)
Historická pozn.
2018
Veřejná pozn.
2018

D Chemikálie a léčiva
D12.644 peptidy 1 380
D12.644.276.374 cytokiny 2 153
D12.644.276.374.750 tumor nekrotizující faktory 371
D12.644.276.374.750.030 antigeny CD70
D12.644.276.374.750.061 faktor aktivující B-buňky 37
D12.644.276.374.750.065 ligand 4-1BB 1
D12.644.276.374.750.092 ligand CD30 2
D12.644.276.374.750.124 ligand CD40 23
D12.644.276.374.750.155 cytokin TWEAK 2
D12.644.276.374.750.186 ektodysplasiny 4
D12.644.276.374.750.249 ligand Fas 18
D12.644.276.374.750.500 lymfotoxin-alfa 17
D12.644.276.374.750.515 lymfotoxin-beta
D12.644.276.374.750.531 ligand OX40 1
D12.644.276.374.750.562 ligand RANK 142
D12.644.276.374.750.625 protein TRAIL 38
D12.644.276.374.750.626 TNF-alfa 1 305
D12.644.276.374.750.656 protein TALL-2 2
D12.644.276.374.750.690 protein TNFSF14
D12.644.276.374.750.720 ligand TL1
D12.776 proteiny 2 575
D12.776.467.374 cytokiny 2 153
D12.776.467.374.750 tumor nekrotizující faktory 371
D12.776.467.374.750.030 antigeny CD70
D12.776.467.374.750.061 faktor aktivující B-buňky 37
D12.776.467.374.750.065 ligand 4-1BB 1
D12.776.467.374.750.092 ligand CD30 2
D12.776.467.374.750.124 ligand CD40 23
D12.776.467.374.750.155 cytokin TWEAK 2
D12.776.467.374.750.186 ektodysplasiny 4
D12.776.467.374.750.249 ligand Fas 18
D12.776.467.374.750.500 lymfotoxin-alfa 17
D12.776.467.374.750.515 lymfotoxin-beta
D12.776.467.374.750.531 ligand OX40 1
D12.776.467.374.750.562 ligand RANK 142
D12.776.467.374.750.625 protein TRAIL 38
D12.776.467.374.750.626 TNF-alfa 1 305
D12.776.467.374.750.656 protein TALL-2 2
D12.776.467.374.750.690 protein TNFSF14
D12.776.467.374.750.710 ligand TL1
D23.529.374 cytokiny 2 153
D23.529.374.750.030 antigeny CD70
D23.529.374.750.061 faktor aktivující B-buňky 37
D23.529.374.750.065 ligand 4-1BB 1
D23.529.374.750.092 ligand CD30 2
D23.529.374.750.124 ligand CD40 23
D23.529.374.750.155 cytokin TWEAK 2
D23.529.374.750.186 ektodysplasiny 4
D23.529.374.750.249 ligand Fas 18
D23.529.374.750.500 lymfotoxin-alfa 17
D23.529.374.750.515 lymfotoxin-beta
D23.529.374.750.531 ligand OX40 1
D23.529.374.750.562 ligand RANK 142
D23.529.374.750.625 protein TRAIL 38
D23.529.374.750.626 TNF-alfa 1 305
D23.529.374.750.656 protein TALL-2 2
D23.529.374.750.690 protein TNFSF14
D23.529.374.750.710 ligand TL1