Bioink: a 3D-bioprinting tool for anticancer drug discovery and cancer management
Language English Country Great Britain, England Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
PubMed
33741496
DOI
10.1016/j.drudis.2021.03.010
PII: S1359-6446(21)00144-6
Knihovny.cz E-resources
- MeSH
- Printing, Three-Dimensional * MeSH
- Bioprinting * MeSH
- Humans MeSH
- Neoplasms drug therapy MeSH
- Drug Discovery * MeSH
- Antineoplastic Agents therapeutic use MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- Names of Substances
- Antineoplastic Agents MeSH
'Bioinks' are important tools for the fabrication of artificial living-tissue constructs that are able to mimic all properties of native tissues via 3D bioprinting technologies. Bioinks are most commonly made by incorporating live cells of interest within a natural or synthetic biocompatible polymeric matrix. In oncology research, the ability to recreate a tumor microenvironment (TME) using by 3D bioprinting constitutes a promising approach for drug development, screening, and in vitro cancer modeling. Here, we review the different types of bioink used for 3D bioprinting, with a focus on its application in cancer management. In addition, we consider the fabrication of bioink using customized materials/cells and their properties in the field of cancer drug discovery.
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