BACKGROUND: The majority of childhood cancer survivors are at risk of treatment-related adverse health outcomes. Survivorship care to mitigate these late effects is endorsed, but it is not available for many adult survivors of childhood cancer in Europe. The PanCareFollowUp project was initiated to improve their health and quality of life (QoL) by facilitating person-centred survivorship care. METHODS: The PanCareFollowUp consortium was established in 2018, consisting of 14 project partners from ten European countries, including survivor representatives. The consortium will develop two PanCareFollowUp Interventions, including a person-centred guideline-based model of care (Care Intervention) and eHealth lifestyle coaching (Lifestyle Intervention). Their development will be informed by several qualitative studies and systematic reviews on barriers and facilitators for implementation and needs and preferences of healthcare providers (HCPs) and survivors. Implementation of the PanCareFollowUp Care Intervention as usual care will be evaluated prospectively among 800 survivors from Belgium, Czech Republic, Italy and Sweden for survivor empowerment, detection of adverse health conditions, satisfaction among survivors and HCPs, cost-effectiveness and feasibility. The feasibility of the PanCareFollowUp Lifestyle Intervention will be evaluated in the Netherlands among 60 survivors. RESULTS: Replication manuals, allowing for replication of the PanCareFollowUp Care and Lifestyle Intervention, will be published and made freely available after the project. Moreover, results of the corresponding studies are expected within the next five years. CONCLUSIONS: The PanCareFollowUp project is a novel European collaboration aiming to improve the health and QoL of all survivors across Europe by developing and prospectively evaluating the person-centred PanCareFollowUp Care and Lifestyle Interventions.

Childhood Cancer International Europe Servitengasse 5 16 Vienna 1090 Austria

Childhood Cancer Research Group Danish Cancer Society Research Centre Strandboulevarden 49 Copenhagen 2100 Denmark

Childhood Cancer Research Group Danish Cancer Society Research Centre Strandboulevarden 49 Copenhagen 2100 Denmark; Department of Clinical Medicine Faculty of Health Aarhus University and Aarhus University Hospital Palle Juul Jensens Boulevard 82 Aarhus 8200 Denmark

Childhood Cancer Research Group Danish Cancer Society Research Centre Strandboulevarden 49 Copenhagen 2100 Denmark; Institute of Social and Preventive Medicine University of Bern Mittelstrasse 43 Bern 3012 Switzerland

Department of Health Technology and Services Research Technical Medical Centre University of Twente P O Box 217 Enschede 7500 AE the Netherlands

Department of Oncology Paediatric Oncology KU Leuven Department of Paediatric Haematology and Oncology University Hospitals Leuven Herestraat 49 Leuven 3000 Belgium

Epidemiology and Biostatistics Unit and DOPO Clinic IRCCS Istituto Giannina Gaslini Via G Gaslini 5 Genoa 16147 Italy

European Society for Paediatric Oncology C o BLSI Clos Chapelle aux Champs 30 Bte 1 30 30 Brussels BE 1200 Belgium

International Clinical Research Centre at St Anne's University Hospital Masaryk University Pekařská 53 Brno 656 91 Czech Republic

Lund University Skane University Hospital Department of Clinical Sciences Lund Oncology Lasarettsgatan 40 Lund 221 85 Sweden

Lund University Skane University Hospital Department of Clinical Sciences Lund Paediatrics Lasarettsgatan 40 Lund 221 85 Sweden

Netherlands Institute for Health Services Research P O Box 1568 Utrecht 3500 BN the Netherlands

Netherlands Institute for Health Services Research P O Box 1568 Utrecht 3500 BN the Netherlands; University of Eastern Finland Department of Health and Social Management P O Box 1627 Kuopio FI 70211 Finland

Newcastle University Centre for Cancer Wolfson Childhood Cancer Research Centre Herschel Building Brewery Lane Newcastle Upon Tyne NE1 7RU United Kingdom; Great North Children's Hospital Royal Victoria Infirmary Queen Victoria Road Newcastle Upon Tyne NE1 4 LP United Kingdom; Translational and Clinical Research Institute Wolfson Childhood Cancer Research Centre Herschel Building Brewery Lane Newcastle Upon Tyne NE1 7RU United Kingdom

Pintail Limited 77 Springhill Avenue Blackrock Dublin Ireland

Population Health Sciences Institute Newcastle University Sir James Spence Institute Royal Victoria Infirmary Queen Victoria Road Newcastle Upon Tyne NE1 4LP United Kingdom; Newcastle University Centre for Cancer Wolfson Childhood Cancer Research Centre Herschel Building Brewery Lane Newcastle Upon Tyne NE1 7RU United Kingdom

Princess Máxima Centre for Paediatric Oncology Heidelberglaan 25 Utrecht 3584 CS the Netherlands

Princess Máxima Centre for Paediatric Oncology Heidelberglaan 25 Utrecht 3584 CS the Netherlands; Department of Paediatrics Emma Children's Hospital Amsterdam UMC Meibergdreef 9 Amsterdam 1105 AZ the Netherlands; Faculty of Medicine Utrecht University and Utrecht Medical Centre Universiteitsweg 98 Utrecht 3584 CG the Netherlands

Princess Máxima Centre for Paediatric Oncology Heidelberglaan 25 Utrecht 3584 CS the Netherlands; PanCare Jacobus Bellamylaan 16 Bussum 1401 AZ the Netherlands

Radboud University Medical Centre Radboud Institute for Health Sciences Department of Hematology Geert Grooteplein Zuid 10 Nijmegen 6525 GA the Netherlands

Radboud University Medical Centre Radboud Institute for Health Sciences Scientific Institute for Quality of Healthcare Geert Grooteplein 21 Nijmegen 6525 EZ the Netherlands

St Anna Children's Hospital Kinderspitalgasse 6 Vienna 1090 Austria; Kepler University Clinic Department of Pediatric and Adolescent Medicine Krankenhausstraße 26 30 Linz 4020 Austria

University of Lucerne Department of Health Sciences and Medicine Frohburgstrasse 3 P O Box 4466 Lucerne 6002 Switzerland

Citace poskytuje Crossref.org

Efficacy of the PanCareFollowUp eHealth Lifestyle Intervention for Survivors of Childhood, Adolescent and Young Adult Cancer

Healthcare providers' expected barriers and facilitators to the implementation of person-centered long-term follow-up care for childhood cancer survivors: A PanCareFollowUp study

Person-centred online lifestyle coaching in childhood, adolescent, and young adult cancer survivors: protocol of the multicentre PanCareFollowUp lifestyle intervention feasibility study

Evaluating the feasibility, effectiveness and costs of implementing person-centred follow-up care for childhood cancer survivors in four European countries: the PanCareFollowUp Care prospective cohort study protocol

Immunosenescence in Childhood Cancer Survivors and in Elderly: A Comparison and Implication for Risk Stratification