Progress in forensic bone DNA analysis: Lessons learned from ancient DNA
Jazyk angličtina Země Nizozemsko Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem, přehledy
PubMed
34265517
DOI
10.1016/j.fsigen.2021.102538
PII: S1872-4973(21)00076-4
Knihovny.cz E-zdroje
- Klíčová slova
- Ancient DNA, Degraded DNA, Forensic, Inhibitors,
- MeSH
- DNA fingerprinting MeSH
- DNA * genetika MeSH
- lidé MeSH
- nekrotická degradace DNA MeSH
- senioři MeSH
- soudní genetika MeSH
- starobylá DNA * MeSH
- Check Tag
- lidé MeSH
- senioři MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
- Názvy látek
- DNA * MeSH
- starobylá DNA * MeSH
Research on ancient and forensic DNA is related in many ways, and the two fields must deal with similar obstacles. Therefore, communication between these two communities has the potential to improve results in both research fields. Here, we present the insights gained in the ancient DNA community with regard to analyzing DNA from aged skeletal material and the potential use of the developed protocols in forensic work. We discuss the various steps, from choosing samples for DNA extraction to deciding between classical PCR amplification and massively parallel sequencing approaches. Based on the progress made in ancient DNA analyses combined with the requirements of forensic work, we suggest that there is substantial potential for incorporating ancient DNA approaches into forensic protocols, a process that has already begun to a considerable extent. However, taking full advantage of the experiences gained from ancient DNA work will require comparative studies by the forensic DNA community to tailor the methods developed for ancient samples to the specific needs of forensic studies and case work. If successful, in our view, the benefits for both communities would be considerable.
Citace poskytuje Crossref.org
