Genetic Recombination in Treponema pallidum: Implications for Diagnosis, Epidemiology, and Vaccine Development
Language English Country United States Media print
Document type Editorial
PubMed
34618784
DOI
10.1097/olq.0000000000001497
PII: 00007435-202201000-00020
Knihovny.cz E-resources
- MeSH
- Bacterial Vaccines genetics MeSH
- Humans MeSH
- Recombination, Genetic MeSH
- Syphilis * diagnosis epidemiology prevention & control MeSH
- Treponema pallidum * genetics MeSH
- Vaccine Development MeSH
- Check Tag
- Humans MeSH
- Publication type
- Editorial MeSH
- Names of Substances
- Bacterial Vaccines MeSH
Department of Biology Masaryk University Brno Czech Republic
From the Department of Mycology Bacteriology Institute of Tropical Medicine Pedro Kourí Havana Cuba
See more in PubMed
Awadalla P. The evolutionary genomics of pathogen recombination. Nat Rev Genet 2003; 4:50–60.
Nechvátal L, Pětrošová H, Grillová L, et al. Syphilis-causing strains belong to separate SS14-like or Nichols-like groups as defined by multilocus analysis of 19 Treponema pallidum strains. Int J Med Microbiol 2014; 304:645–653.
Šmajs D, Strouhal M, Knauf S. Genetics of human and animal uncultivable treponemal pathogens. Infect Genet Evol 2018; 61:92–107.
Šmajs D, Strouhal M. Uncultivable pathogenic Treponemes. In: Tang YW, Sussman M, Liu D, et al, eds. Molecular Medical Microbiology, 2nd ed. Amsterdam, The Netherlands: Elsevier Science Ltd., 2015:1421–1436.
Schell RF, Musher DM, eds. Rabbit and hamster models of treponemal infection, p 121–135. In: Pathogenesis and immunology of treponemal infection. New York., NY: Marcel Dekker, Inc.
Turner TB, Hollander DH. Monograph no. 35, 1–278. Geneva, Switzerland: World Health Organization, 1957.
Edmondson DG, DeLay BD, Kowis LE, et al. Parameters affecting continuous in vitro culture of Treponema pallidum strains. MBio 2021; 12:e03536–e03520.
Grillová L, Oppelt J, Mikalová L, et al. Directly sequenced genomes of contemporary strains of syphilis reveal recombination-driven diversity in genes encoding predicted surface-exposed antigens. Front Microbiol 2019; 10:1691.
Maděránková D, Mikalová L, Strouhal M, et al. Identification of positively selected genes in human pathogenic treponemes: Syphilis-, yaws-, and bejel-causing strains differ in sets of genes showing adaptive evolution. PLoS Negl Trop Dis 2019; 13:e0007463.
Brinkman MB, McGill MA, Pettersson J, et al. A novel Treponema pallidum antigen, TP0136 , is an outer membrane protein that binds human fibronectin. Infect Immun 2008; 76:1848–1857.
Arora N, Schuenemann VJ, Jäger G, et al. Origin of modern syphilis and emergence of pandemic Treponema pallidum cluster. Nat Microbiol 2016; 2:16245.
Kumar S, Caimano MJ, Anand A, et al. Sequence variation of rare outer membrane protein-barrel domains in clinical strains provides insights into the evolution of Treponema pallidum subsp. pallidum , the syphilis spirochete. MBio 2018; 9:e01006–e01018.
Röltgen K, Pluschke G. Buruli ulcer: The efficacy of innate immune defense may be a key determinant for the outcome of infection with Mycobacterium ulcerans . Front Microbiol 2020; 11:1018. doi:doi.org/10.3389/fmicb.2020.01018.
Brzuszkiewicz E, Thürmer A, Schuldes J, et al. Genome sequence analyses of two isolates from the recent Escherichia coli outbreak in Germany reveal the emergence of a new pathotype: Entero-aggregative-haemorrhagic Escherichia coli (EAHEC). Arch Microbiol 2011; 193:883–891.
Munhoz D, Santos F, Mitsunari T, et al. Hybrid atypical enteropathogenic and extraintestinal Escherichia coli (aEPEC/ExPEC) BA1250 strain: A draft genome. Pathogens 2021; 10:475.
Kouri V, Khouri R, Alemán Y, et al. CRF19_cpx is an evolutionary fit HIV-1 variant strongly associated with rapid progression to AIDS in Cuba. EBioMedicine 2015; 2:244–254.
Pérez L, Thomson MM, Bleda MJ, et al. HIV type 1 molecular epidemiology in Cuba: High genetic diversity, frequent mosaicism, and recent expansion of BG intersubtype recombinant forms. AIDS Res Hum Retrovir 2006; 22:724–733.
Noda AA, Rodríguez I, Grillová L, et al. Accuracy of PCR and serological testing for the diagnosis of primary syphilis: Both tests are necessary. Int J STD AIDS 2019; 30:1087–1094.
Knauf S, Luert S, Šmajs D, et al. Gene target selection for loop-mediated isothermal amplification for rapid discrimination of Treponema pallidum subspecies. PLoS Negl Trop Dis 2018; 12:e0006396.
Marks M, Katz S, Chi KH, et al. Failure of PCR to detect Treponema pallidum ssp pertenue DNA in blood in latent yaws. PLoS Negl Trop Dis 2015; 9:e0003905.
Strouhal M, Mikalová L, Haviernik J, et al. Complete genome sequences of two strains of Treponema pallidum subsp pertenue from Indonesia: Modular structure of several treponemal genes. PLoS Negl Trop Dis 2018; 12:e0006867.
Chi KH, Danavall D, Taleo F, et al. Molecular differentiation of Treponema pallidum subspecies in skin ulceration clinically suspected as yaws in Vanuatu using real-time multiplex PCR and serological methods. Am J Trop Med Hyg 2015; 92:134–138.
Van Voorhis WC, Barrett LK, Lukehart SA, et al. Serodiagnosis of syphilis: Antibodies to recombinant Tp0453, Tp92, and Gpd proteins are sensitive and specific indicators of infection by Treponema pallidum . J Clin Microbiol 2003; 41:3668–3674.
Smith BC, Simpson Y, Morshed MG, et al. New proteins for a new perspective on syphilis diagnosis. J Clin Microbiol 2013; 51:105–111.
Jiang C, Zhao F, Xiao J, et al. Evaluation of the recombinant protein TpF1 of Treponema pallidum for Serodiagnosis of syphilis. Clin Vaccine Immunol 2013; 20:1563–1568.
Grillová L, Bawa T, Mikalová L, et al. Molecular characterization of Treponema pallidum subsp pallidum in Switzerland and France with a new multilocus sequence typing scheme. PLoS One 2018; 13:e0200773.
Noda AA, Rodríguez I, Šmajs D. Genotyping of Treponema pallidum in Cuba (2018-2019): Increased circulation of recombinant genotype and no new Treponema pallidum subspecies endemicum infection among syphilis patients. Sex Transm Dis 2020; 47:e39–e41.
Hemelaar J, Elangovan R, Yun J, et al. Global and regional molecular epidemiology of HIV-1, 1990–2015: A systematic review, global survey, and trend analysis. Lancet Infect Dis 2019; 19:143–155.
Yahara K, Nakayama S, Shimuta K, et al. Genomic surveillance of Neisseria gonorrhoeae to investigate the distribution and evolution of antimicrobial-resistance determinants and lineages. Microb Genom 2018; 4:e000205.
Hook EW 3rd. Syphilis. Lancet 2017; 389:1550–1557.
