The purpose of this review is to discuss rare neurological disorders with respect to communication difficulties typical of children. Firstly, communication disorders with special focus on rare communication neurological disorders are discussed. Secondly, on the basis of literature review, the authors explore clinical studies on the most typical rare children's communication neurological disorders. Thirdly, on the basis of the findings from the clinical studies, they set a few recommendations for their medical therapies and management. The methodology was based on the literature review of research studies exploring the research issue. The findings show that the intervention strategies appear to have positive effects on the improvement of speech and language production among children suffering from Landau-Kleffner syndrome and childhood apraxia of speech. Nevertheless, randomized control trials are needed in order to accelerate and facilitate an early and relevant diagnosis and treatment management. In addition, a multidisciplinary approach seems to be the most appropriate for the accurate diagnosis and comprehensive treatment.

Charles University Prague 2nd Faculty of Medicine and University Hospital Motol Memory Disorders Clinic Department of Neurology Prague Czech Republic

St Anne's University Hospital Brno International Clinical Research Center Brno Czech Republic

University Hospital Hradec Kralove Biomedical Research Centre Hradec Kralove Czech Republic

University Hospital Hradec Kralove Department of Neurology Hradec Kralove Czech Republic

University of Hradec Kralove Faculty of Science Department of Chemistry Hradec Kralove Czech Republic

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Aime S, Bellet B, Rath A (2015). Rare diseases in ICD 11: Making rare diseases visible in health information systems through appropriate coding. Orphanet J Rare Dis 10, 35. DOI: 10.1186/s13023-015-0251-8. PubMed DOI

ASHA (1982). Definitions-communicative disorders and variations. American Speech-Language-Hearing Association. 24(11): 949-950.

ASHA (2017). Childhood apraxia of speech. [online] [cit. 2017-12-20]. Available from: http://www.asha.org/PRPSpecificTopic.aspx?folderid=8589935338§ion=Treatment.

Beathard B, Krout RE (2008). A music therapy clinical case study of a girl with childhood apraxia of speech. The Arts in Psychotherapy. 35(2): 107-116. DOI: 10.1016/j.aip.2008.01.004. DOI

Campbell TF (2003). Childhood apraxia of speech: Clinical symptoms and speech characteristics. In: Shriberg LD, Campbell TF (Eds). Proceedings of the 2002 Childhood Apraxia of Speech Symposium. The Hendrix Foundation, Carlsbad, pp. 37-40.

Dale PS, Hayden DA (2013). Treating speech subsystems in childhood apraxia of speech with tactual input: the PROMPT approach. Am J Speech Lang Pathol 22(4): 644-666. DOI: 10.1044/1058-0360(2013/12-0055). PubMed DOI

Dodel R, Peter H, Walbert T, Spottke A, Noelker C, Berger K, et al. (2004). The socioeconomic impact of narcolepsy. Sleep 27(6): 1123-1128. PubMed DOI

European Commission on Public Health (2017). Useful information on rare diseases from an EU perspective. [online] [cit. 2017-12-20]. Available from: http://ec.europa.eu/health/ph_information/documents/ev20040705_rd05_en.pdf

Fandino M, Connoly M, Usher L, Palm S, Kosak FK (2011). Landau/Kleffner syndrome: a rare auditory processing disorder series of cases and review of the literature. Int J Pediatr Otorhinolaryngol 75: 33-38. DOI: 10.1016/j.ijporl.2010.10.001. PubMed DOI

Federico A (2013). Rare neurological diseases: a Pandora's box for neurology (an European and Italian perspective). Rev Neurol 169(Suppl. 1): S12-S17. DOI: 10.1016/S0035-3787(13)70054-7. PubMed DOI

Guevara-Campos J, González-de Guevara L (2007). Landau-Kleffner syndrome: an analysis of 10 cases in Venezuela. Rev Neurol 44(11): 652-656. DOI

Hession CE, Eastwood B, Watterson D, Lehane CM, Oxley N, Murphy BA (2014). Therapeutic horse riding improves cognition, mood arousal, and ambulation in children with dyspraxia. J Altern Complement Med 20(1): 19-23. DOI: 10.1089/acm.2013.0207. PubMed DOI

Kleffner FR, Landau WM (2009). The Landau-Kleffner syndrome. Epilepsia 50(Suppl. 7): 4. PubMed DOI

Klimova B, Kuca K (2016a). Speech and language impairments in dementia - a mini-review. J Appl Biomed 14(2): 97-103. DOI: 10.1016/j.jab.2016.02.002. DOI

Klimova B, Kuca K (2016b). Multi-nutrient dietary intervention approach to the management of Alzheimer's disease - a mini-review. Curr Alzheimer Res 13(12): 1312-1318. PubMed DOI

Klimova B, Maresova P, Valis M, Hort J, Kuca K (2015). Alzheimer's disease and language impairments: Social intervention and medical treatment. Clin Interv Aging 10: 1401-1408. DOI: 10.2147/CIA.S89714. PubMed DOI

Kossoff EH, Los JG, Boatman DF (2007). A pilot study transitioning children onto levetiracetam monotherapy to improve language dysfunction associated with benign rolandic epilepsy. Epilepsy Behav 11(4): 514-517. DOI: 10.1016/j.yebeh.2007.07.011. PubMed DOI

Krapp KM (2002). The Gale Encyclopedia of Nursing & Allied Health. 6th edition. Gale Group, Detroit.

Kubackova K, et al. (2014). Vzacna onemocneni v kostce. [Rare Diseases in a Nutshell.] Mlada fronta, a. s., Praha (Czech).

Lewis BA, Freebairn LA, Hansen A, Taylor HG, Iyengar SK, Shriberg LD (2004). Family pedigrees of children with suspected childhood apraxia of speech. J Commun Disord 37: 157-175. DOI: 10.1016/j.jcomdis.2003.08.003. PubMed DOI

Li Z, Gao Z, Jin C, Guo Q, Wang L, Shandan W, et al. (2014). The efficacy of leviteracetam versus carbamazepine for epilepsy: a meta-analysis. Iran J Public Health 43(12): 1616-1626.

Longe JL (2011). The Gale Encyclopedia of Children's Health: Infancy through Adolescence. 2nd ed. Gale Group, Detroit.

Lotte N (2006). The pathophysiological mechanisms of cognitive and behavioral disturbances in children with Landau-Kleffner syndrome or epilepsy with continuous spike-and-waves during slow-wave sleep. Seizure 15: 249-258. DOI: 10.1016/j.seizure.2006.02.008. PubMed DOI

Ludlow CL (2011). Spasmodic dysphonia: a laryngeal control disorder specific to speech. The J Neurosci 31(3): 793-797. DOI: 10.1523/JNEUROSCI.2758-10.2011. PubMed DOI

Maas E, Butalla CE, Farinella KA (2012). Feedback frequency in treatment for childhood apraxia of speech. Am J Speech Lang Pathol 21(3): 239-257. DOI: 10.1044/1058-0360(2012/11-0119). PubMed DOI

Maas E, Farinella KA (2012). Random versus blocked practice in treatment for childhood apraxia of speech. J Speech Lang Hear Res 55(2): 561-578. DOI: 10.1044/1092-4388(2011/11-0120). PubMed DOI

Maresova P, Klimova B, Kuca K (2016). Financial and legislative aspects of drug development of orphan diseases on the European market - a systematic review. Applied Economics 48(27): 2562-2570. DOI: 10.1080/00036846.2015.1125433. DOI

Marien P, Verhoeven J (2007). Cerebellar involvement in motor speech planning: some further evidence from foreign accent syndrome. Folia Phoniatr Logop 59(4): 210-217. DOI: 10.1159/000102933. PubMed DOI

Melby-Lervåg M, Hulme C (2013). Is working memory training effective? A meta-analytic review. Dev Psychol 49(2): 270-291. DOI: 10.1037/a0028228. PubMed DOI

Melby-Lervåg M, Hulme C (2016). There is no convincing evidence that working memory training is effective: A reply to Au et al. (2014) and Karbach and Verhaeghen (2014). Psychon Bull Rev 23(1): 324-330. DOI: 10.3758/s13423-015-0862-z. PubMed DOI

Mikati MA, Shamseddine AN (2005). Management of Landau-Kleffner syndrome. Paediatr Drugs 7(6): 377-389. PubMed DOI

Murray E, McCabe P, Ballard KJ (2012). A comparison of two treatments for childhood apraxia of speech: methods and treatment protocol for a parallel group randomized control study. BMC Pediatr 12: 112. DOI: 10.1186/1471-2431-12-112. PubMed DOI

Murray E, McCabe P, Ballard KJ (2014). A systematic review of treatment outcomes for children with childhood apraxia of speech. Am J Speech Lang Pathol 23(3): 486-504. DOI: 10.1044/2014_AJSLP-13-0035. PubMed DOI

Orphanet (2009). Jacobsen syndrome. [online] [cit. 2017-12-20]. Available from: http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=2308

Preston JL, Brick N, Landi N (2013). Ultrasound biofeedback treatment for persisting childhood apraxia of speech. Am J Speech Lang Pathol 22(4): 627-643. DOI: 10.1044/1058-0360(2013/12-0139). PubMed DOI

Rare Diseases Act of 2002 (2002). [online] [cit. 2017-12-20]. Available from: https://www.gpo.gov/fdsys/pkg/PLAW-107publ280/html/PLAW-107publ280.htm

Sinclair DB, Snyder TJ (2005). Corticosteroids for the treatment of Landau-Kleffner syndrome and continuous spike-wave discharge during sleep. Pediatr Neurol 32(5): 300-306. DOI: 10.1016/j.pediatrneurol.2004.12.006. PubMed DOI

Thomas DC, McCabe P, Ballard KJ (2014). Rapid Syllable Transitions (ReST) treatment for childhood apraxia of speech: the effect of lower dose-frequency. J Commun Disord 51: 29-42. DOI: 10.1016/j.jcomdis.2014.06.004. PubMed DOI

Tisch SHD, Brake HM, Law M, Cole IE, Darveniza P (2003). Spasmodic dysphonia: clinical features and effects of botulinium toxin therapy in 169 patients - an Australian experience. J Clin Neurosci 10(4): 434-438. PubMed DOI

Velleman SL (2003). Childhood apraxia of speech: Resource guide. Thomson, New York.

Winter J (2008). Critical review: evidence of the presence of literacy difficulties in children who have childhood apraxia of speech. [online] [cit. 2017-12-20]. Available from: https://www.uwo.ca/fhs/lwm/ebp/reviews/2007-08/Winter,MJ.pdf