This study presents the activity of a series of 1,8-naphthalimide-carborane/metallacarborane conjugates against Rhabditis sp. The carborane conjugates were the least active. Selected conjugates with cobaltacarborane (5 and 6) showed high activity. Their lethal concentration (LC50) values are substantially lower than that of the drug mebendazole.

Chair and Department of Biology and Genetics Medical University of Lublin 4a Chodźki St Lublin 20 093 Poland

Chair of Pharmacology and Biology Department of Pharmacology Medical University of Lublin 4a Chodźki St Lublin 20 093 Poland

Institute of Inorganic Chemistry Czech Academy of Sciences Hlavní 1001 CZ 250 68 Řež Czech Republic

Institute of Medical Biology Polish Academy of Sciences 106 Lodowa St Lodz 93 232 Poland

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