Department of Hemato oncology Institute of Molecular Genetics of the Czech Academy of Sciences Prague 142 00 Czech Republic; Childhood Leukaemia Investigation Prague Department of Pediatric Haematology and Oncology 2nd Faculty of Medicine Charles University Prague University Hospital Motol Prague 150 06 Czech Republic

Department of Medicine Division Hematology Oncology University of Alabama at Birmingham Birmingham AL 35294 USA

Harvard Stem Cell Institute Harvard Medical School Boston MA 02115 USA; Cancer Science Institute National University of Singapore Singapore 117599 Singapore

Hematology Division Department of Medical Images Hematology and Clinical Oncology Ribeirão Preto Medical School University of São Paulo Ribeirão Preto SP 14048 900 Brazil

Stem Cell Reports. 2021 Aug 10;16(8):1999-2013. doi: 10.1016/j.stemcr.2021.06.008. PubMed

Stem Cell Reports. 2022 Mar 8;17(3):443-445. doi: 10.1016/j.stemcr.2022.02.006. PubMed

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Lang P., Teltschik H.M., Feuchtinger T., Müller I., Pfeiffer M., Schumm M., Ebinger M., Schwarze C.P., Gruhn B., Schrauder A., et al. Transplantation of CD3/CD19 depleted allografts from haploidentical family donors in paediatric leukaemia. Br. J. Haematol. 2014;165:688–698. PubMed

Lobo de Figueiredo-Pontes L., Adamcova M.K., Grusanovic S., Kuzmina M., Aparecida Lopes I., Fernandes de Oliveira Costa A., Zhang H., Strnad H., Lee S., Moudra A., et al. Improved hematopoietic stem cell transplantation upon inhibition of natural killer cell-derived interferon-gamma. Stem Cell Reports. 2021;16:1999–2013. PubMed PMC

Locatelli F., Merli P., Pagliara D., Li Pira G., Falco M., Pende D., Rondelli R., Lucarelli B., Brescia L.P., Masetti R., et al. Outcome of children with acute leukemia given HLA-haploidentical HSCT after αβ T-cell and B-cell depletion. Blood. 2017;130:677–685. PubMed

Merli P., Pagliara D., Galaverna F., Li Pira G., Andreani M., Leone G., Amodio D., Pinto R.M., Bertaina A., Bertaina V., et al. TCRαβ/CD19 depleted HSCT from an HLA-haploidentical relative to treat children with different non-malignant disorders. Blood Adv. 2021;6:281–292. PubMed PMC

Merli P., Eichholz T., Catanoso M.L., Lang P., Locatelli F. NK cell content does not seem to influence engraftment in ex vivo T cell depleted haploidentical stem cell transplantation. Stem Cell Reports. 2022;17:443–445. PubMed PMC