INTRODUCTION: An analysis on the ECLS use for patients with respiratory or cardiac support in COVID-19 based on an international response to EuroELSO survey, aims to generate a more comprehensive understanding of ECLS role during the recent viral pandemic. METHODS: EuroELSO announced the survey at the 10th annual congress in London, May 2022. The survey covered 26 multiple-choice questions. RESULTS: The survey returned 69 questionnaires from 62 centers across 22 European countries and seven centers across five non-European countries. Most of the centers providing ECLS for COVID-19 patients had more than 30 runs for respiratory support since December 2019. In the same period, at least 31 runs in adult COVID-19 patients have been performed in 48 of 69 centers (69.6%). The reported pediatric data from 18 centers is limited to less than the patients per center. CONCLUSION: Majority of the COVID-19 patients received respiratory ECLS support and adult patients dominated. The indications and contraindications are broadly aligned with available guidelines. Most of the centers considered age >65 or biological age as a relative or absolute contraindication for ECLS in COVID-19. ECLS withdrawal criteria in COVID-19 are controversial because the long-term outcomes after ECLS in COVID-19 and the impact of critical illness and the impact of long-COVID are still not known.

2nd Department of Internal Cardiovascular Medicine General University Hospital Prague Czech Republic

Birmingham Women´s and Children´s NHS Foundation Trust Birmingham UK

Cardio Thoracic Surgery Department Maastricht University Medical Center Maastricht The Netherlands

Centre for Human and Applied Physiological Sciences King's College London London UK

Critical Care Department Vall d´Hebron University Hospital; SODIR Vall d´Hebron Research Institute Barcelona Spain

Department of Biomedical Metabolic and Neural Sciences University of Modena and Reggio Emilia Modena Italy

Department of Critical Care Guy's and St Thomas' NHS Foundation Trust London UK

Department of Critical Care Royal Papworth NHS Foundation Trust Cambridge UK

Department of Internal Medicine 2 Universitätsklinikum Regensburg Regensburg Germany

Department of Perfusion University Hospital Gasthuisberg Leuven Belgium

Department of Respiratory Medicine Paracelsus Medical University Nuremberg Germany

ECMO Centre Karolinska Department of Pediatric Perioperative Medicine and Intensive Care Karolinska University Hospital Stockholm Sweden

Intensive Care Unit Maurizio Bufalini Hospital Cesena Italy

Paediatric Intensive care Leiden University Medical Center Leiden The Netherlands

Pediatric Intensive Care Unit Children's Hospital Bambino Gesù Rome Italy

UOC AR2 Anestesia e Terapia Intensiva Cardiotoracica Fondazione IRCCS Policlinico San Matteo Pavia Italy

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Barbaro RP, MacLaren G, Boonstra PS, et al.Extracorporeal membrane oxygenation for COVID-19: evolving outcomes from the international extracorporeal life support organization registry. Lancet 2021; 398: 1230–1238. PubMed PMC

Lorusso R, Combes A, Lo Coco V, et al.ECMO for COVID-19 patients in Europe and Israel. Intensive Care Med 2021; 47: 344–348. PubMed PMC

Mang S, Kalenka A, Broman LM, et al.Extracorporeal life support in COVID-19-related acute respiratory distress syndrome: A EuroELSO international survey. Artif Organs 2021; 45: 495–505. PubMed PMC

Swol J, Lorusso R. Additive treatment considerations in COVID-19 - the clinician´s perspective on extracorporeal adjunctive purification techniques. Artif Organs 2020; 9: 918–925. PubMed PMC

Martucci G, Słomka A, Lebowitz SE, et al.COVID-19 and Extracorporeal Membrane Oxygenation. Adv Exp Med Biol 2021; 1353: 173–195. PubMed

Puslecki M, Dabrowski M, Baumgart K, et al.Managing patients on extracorporeal membrane oxygenation support during the COVID-19 pandemic - a proposal for a nursing standard operating procedure. BMC Nurs 2021; 20: 214. PubMed PMC

Barbaro RP, MacLaren G, Swol J, et al.COVID-19 ARDS: getting ventilation right - Authors' reply. Lancet 2022; 399: 22–23. PubMed PMC

Mariani S, De Piero ME, Ravaux JM, et al.Temporary mechanical circulatory support for COVID-19 patients: A systematic review of literature. Artif Organs 2022; 7: 1249–1267. PubMed PMC

Polastri M, Swol J, Loforte A, et al.Extracorporeal membrane oxygenation and rehabilitation in patients with COVID-19: A scoping review. Artif Organs 2022; 46: 30–39. PubMed PMC

Barbaro RP, MacLaren G, Boonstra PS, et al.Extracorporeal membrane oxygenation support in COVID-19: an international cohort study of the Extracorporeal Life Support Organization registry. Lancet 2020; 396: 1071–1078. PubMed PMC

Badulak J, Antonini MV, Stead CM, et al.Extracorporeal Membrane Oxygenation for COVID-19: Updated 2021 Guidelines from the Extracorporeal Life Support Organization. Asaio J 2021; 67: 485–495. PubMed PMC

Swol J, Tonna JE, Lorusso R. A new stick in the bunch of reporting guidelines. Artif Organs 2022; 9: 1725–1726. PubMed

Di Nardo M, De Piero ME, Hoskote A, et al.. EuroECMO neonatal and paediatric COVID-19 Working Group and EuroELSO Steering Committee. Extracorporeal membrane oxygenation in children with COVID-19 and PIMS-TS during the second and third wave. Lancet Child Adolesc Health 2022; 6: e14–e15. PubMed PMC

Di Nardo M, Hoskote A, Thiruchelvam T, et al., EuroELSO Neonatal & Pediatric Working Group & collaborators on COVID-19. Extracorporeal Membrane Oxygenation in Children with Coronavirus Disease 2019: Preliminary Report from the Collaborative European Chapter of the Extracorporeal Life Support Organization Prospective Survey. ASAIO J 2021; 67: 121–124. PubMed PMC