In this special edition (closed on 31 October 2022), 4 reviews, 13 original papers, 1 communication, and 1 case report are published [...].

Department of Molecular Biology and Cell Pathology 3rd Faculty of Medicine Charles University 100 00 Prague Czech Republic

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Chen M., Shi J.L., Zheng Z.M., Lin Z., Li M.Q., Shao J. Galectins: Important Regulators in Normal and Pathologic Pregnancies. Int. J. Mol. Sci. 2022;23:10110. doi: 10.3390/ijms231710110. PubMed DOI PMC

Benkhalifa M., Joao F., Duval C., Montjean D., Bouricha M., Cabry R., Bélanger M.C., Bahri H., Miron P., Benkhalifa M. Endometrium Immunomodulation to Prevent Recurrent Implantation Failure in Assisted Reproductive Technology. Int. J. Mol. Sci. 2022;23:12787. doi: 10.3390/ijms232112787. PubMed DOI PMC

Vilotić A., Nacka-Aleksić M., Pirković A., Bojić-Trbojević Ž., Dekanski D., Jovanović Krivokuća M. IL-6 and IL-8: An Overview of Their Roles in Healthy and Pathological Pregnancies. Int. J. Mol. Sci. 2022;23:14574. doi: 10.3390/ijms232314574. PubMed DOI PMC

Ângelo-Dias M., Martins C., Dias S.S., Borrego L.M., Lima J. Association of B Cells with Idiopathic Recurrent Pregnancy Loss: A Systematic Review and Meta-Analysis. Int. J. Mol. Sci. 2022;23:15200. doi: 10.3390/ijms232315200. PubMed DOI PMC

Ortega M.A., Gómez-Lahoz A.M., Sánchez-Trujillo L., Fraile-Martinez O., García-Montero C., Guijarro L.G., Bravo C., De Leon-Luis J.A., Saz J.V., Bujan J., et al. Chronic Venous Disease during Pregnancy Causes a Systematic Increase in Maternal and Fetal Proinflammatory Markers. Int. J. Mol. Sci. 2022;23:8976. doi: 10.3390/ijms23168976. PubMed DOI PMC

Peñailillo R., Acuña-Gallardo S., García F., Monteiro L.J., Nardocci G., Choolani M.A., Kemp M.W., Romero R., Illanes S.E. Mesenchymal Stem Cells-Induced Trophoblast Invasion Is Reduced in Patients with a Previous History of Preeclampsia. Int. J. Mol. Sci. 2022;23:9071. doi: 10.3390/ijms23169071. PubMed DOI PMC

Martinez-Fierro M.L., Garza-Veloz I., Castañeda-Lopez M.E., Wasike D., Castruita-De la Rosa C., Rodriguez-Sanchez I.P., Delgado-Enciso I., Flores-Mendoza J. Evaluation of the Effect of the Fibroblast Growth Factor Type 2 (FGF-2) Administration on Placental Gene Expression in a Murine Model of Preeclampsia Induced by L-NAME. Int. J. Mol. Sci. 2022;23:10129. doi: 10.3390/ijms231710129. PubMed DOI PMC

Hromadnikova I., Kotlabova K., Krofta L. Cardiovascular Disease-Associated MicroRNAs as Novel Biomarkers of First-Trimester Screening for Gestational Diabetes Mellitus in the Absence of Other Pregnancy-Related Complications. Int. J. Mol. Sci. 2022;23:10635. doi: 10.3390/ijms231810635. PubMed DOI PMC

Czamara D., Cruceanu C., Lahti-Pulkkinen M., Dieckmann L., Ködel M., Sauer S., Rex-Haffner M., Sammallahti S., Kajantie E., Laivuori H., et al. Genome-Wide Copy Number Variant and High-Throughput Transcriptomics Analyses of Placental Tissues Underscore Persisting Child Susceptibility in At-Risk Pregnancies Cleared in Standard Genetic Testing. Int. J. Mol. Sci. 2022;23:11448. doi: 10.3390/ijms231911448. PubMed DOI PMC

Huang Y., Li R., Hu R., Yao J., Yang Y. PEG2-Induced Pyroptosis Regulates the Expression of HMGB1 and Promotes hEM15A Migration in Endometriosis. Int. J. Mol. Sci. 2022;23:11707. doi: 10.3390/ijms231911707. PubMed DOI PMC

Lynch C.S., Kennedy V.C., Tanner A.R., Ali A., Winger Q.A., Rozance P.J., Anthony R.V. Impact of Placental SLC2A3 Deficiency during the First-Half of Gestation. Int. J. Mol. Sci. 2022;23:12530. doi: 10.3390/ijms232012530. PubMed DOI PMC

Misan N., Michalak S., Rzymski P., Poniedziałek B., Kapska K., Osztynowicz K., Ropacka-Lesiak M. Molecular Indicators of Blood-Brain Barrier Breakdown and Neuronal Injury in Pregnancy Complicated by Fetal Growth Restriction. Int. J. Mol. Sci. 2022;23:13798. doi: 10.3390/ijms232213798. PubMed DOI PMC

Mavreli D., Theodora M., Avgeris M., Papantoniou N., Antsaklis P., Daskalakis G., Kolialexi A. First Trimester Maternal Plasma Aberrant miRNA Expression Associated with Spontaneous Preterm Birth. Int. J. Mol. Sci. 2022;23:14972. doi: 10.3390/ijms232314972. PubMed DOI PMC

Szala-Poździej A., Świerzko A.S., Gajek G., Kufelnicka-Babout M., Chojnacka K., Kobiela P., Jarych D., Sobczuk K., Mazela J., Domżalska-Popadiuk I., et al. Association of the FCN2 Gene Promoter Region Polymorphisms with Very Low Birthweight in Preterm Neonates. Int. J. Mol. Sci. 2022;23:15336. doi: 10.3390/ijms232315336. PubMed DOI PMC

Kedziora S.M., Obermayer B., Sugulle M., Herse F., Kräker K., Haase N., Langmia I.M., Müller D.N., Staff A.C., Beule D., et al. Placental Transcriptome Profiling in Subtypes of Diabetic Pregnancies Is Strongly Confounded by Fetal Sex. Int. J. Mol. Sci. 2022;23:15388. doi: 10.3390/ijms232315388. PubMed DOI PMC

Kadife E., Harper A., De Alwis N., Chien K., Hannan N., Brownfoot F.C. SLC38A4 Amino Acid Transporter Expression Is Significantly Lower in Early Preterm Intrauterine Growth Restriction Complicated Placentas. Int. J. Mol. Sci. 2022;24:403. doi: 10.3390/ijms24010403. PubMed DOI PMC

Dymara-Konopka W., Laskowska M., Grywalska E., Hymos A., Błażewicz A., Leszczyńska-Gorzelak B. Similar Pro- and Antiangiogenic Profiles Close to Delivery in Different Clinical Presentations of Two Pregnancy Syndromes: Preeclampsia and Fetal Growth Restriction. Int. J. Mol. Sci. 2023;24:972. doi: 10.3390/ijms24020972. PubMed DOI PMC

Chighine A., Corona A., Catani G., Conte C., Demontis R., Nioi M. A Fatal Case of Metastatic Pulmonary Calcification during the Puerperium. Int. J. Mol. Sci. 2022;23:15131. doi: 10.3390/ijms232315131. PubMed DOI PMC

Sammar M., Apicella C., Altevogt P., Meiri H., Vaiman D. Modeling Preeclampsia In Vitro: Polymorphic Variants of STOX1-A/B Genes Can Downregulate CD24 in Trophoblast Cell Lines. Int. J. Mol. Sci. 2022;23:15927. doi: 10.3390/ijms232415927. PubMed DOI PMC