Barriers to Exercise in Adults With Type 1 Diabetes and Insulin Resistance
Jazyk angličtina Země Kanada Médium print-electronic
Typ dokumentu časopisecké články
PubMed
37121543
DOI
10.1016/j.jcjd.2023.04.016
PII: S1499-2671(23)00097-7
Knihovny.cz E-zdroje
- Klíčová slova
- activité physique, attitudes envers l’exercice, attitudes toward exercise, diabète de type 1, insulin resistance, physical activity, quality of life, qualité de vie, résistance à l’insuline, type 1 diabetes,
- MeSH
- cvičení MeSH
- diabetes mellitus 1. typu * MeSH
- dospělí MeSH
- glukosa MeSH
- hypoglykemie * epidemiologie prevence a kontrola MeSH
- inzulinová rezistence * MeSH
- kvalita života MeSH
- lidé MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- glukosa MeSH
OBJECTIVE: Our aim in this study was to assess attitudes toward exercise and quality of life (QoL) in adults with type 1 diabetes (T1D) with and without insulin resistance (IR). METHODS: We pooled baseline pretreatment data from a subset of individuals with T1D from 2 randomized controlled trials. Estimated glucose disposal rate (eGDR), a validated surrogate marker of IR, was calculated using an established formula to classify individuals according to IR status with a cutpoint of <6 mg/kg/min for the determination of IR. Self-reported barriers to exercise were obtained using a validated questionnaire, the Barriers to Physical Activity in T1D (BAPAD-1). In addition, QoL was determined using the 36-item Short Form (SF-36) questionnaire. Differences between dichotomized variables were assessed using the independent t test, Mann-Whitney U test, or Fisher exact test. Linear regression was employed to explore the association of eGDR with BAPAD-1 and QoL scores, with sequential adjustment for potential confounders. RESULTS: Of the 85 individuals included in our study, 39 were classified as having IR. The mean BAPAD-1 total score was higher for individuals with IR (IR: 3.87±0.61; non-IR: 2.83±0.55; p<0.001). The highest exercise barrier scores for individuals with IR were risk of hypoglycemia (5.67±1.26) and risk of hyperglycemia (5.23±1.20), whereas the highest scoring exercise barrier scores for non-IR individuals were not diabetes-related, with low level of fitness (3.91±1.26) and physical health status, excluding diabetes (3.67±1.48), ranked highest. QoL scores were comparable between groups (p>0.05). CONCLUSIONS: Risk of hypoglycemia was the greatest barrier to exercise in individuals with T1D with IR, whereas non-diabetes-related barriers to exercise were more salient in individuals with T1D without IR.
Department of Internal Medicine 2nd Medical Faculty Charles University Prague Czech Republic
Leeds Institute of Cardiovascular and Metabolic Medicine University of Leeds Leeds United Kingdom
School of Food Science and Nutrition University of Leeds Leeds United Kingdom
Citace poskytuje Crossref.org
