Targeting APRIL in the Treatment of IgA Nephropathy

. 2024 Mar 01 ; 19 (3) : 394-398. [epub] 20231006

Jazyk angličtina Země Spojené státy americké Médium print-electronic

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/pmid37801688
Odkazy

PubMed 37801688
PubMed Central PMC10937009
DOI 10.2215/cjn.0000000000000338
PII: 01277230-202403000-00021
Knihovny.cz E-zdroje

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Lafayette RA Canetta PA Rovin BH, et al. . A randomized, controlled trial of rituximab in IgA nephropathy with proteinuria and renal dysfunction. J Am Soc Nephrol. 2017;28(4):1306–1313. doi:10.1681/ASN.2016060640 PubMed DOI PMC

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Mathur M Barratt J Suzuki Y, et al. . Safety, tolerability, pharmacokinetics, and pharmacodynamics of VIS649 (sibeprenlimab), an APRIL-neutralizing IgG2 monoclonal antibody, in healthy volunteers. Kidney Int Rep. 2022;7(5):993–1003. doi:10.1016/j.ekir.2022.01.1073 PubMed DOI PMC

Kooienga L Suzuki Y Chacko B, et al. . Interim analysis (IA) of a global phase 2 randomized controlled trial of sibeprenlimab (VIS649), an APRIL-neutralizing monoclonal antibody, in IgA nephropathy. Abstract TH-PO991. 2022 American Society of Nephrology Kidney Week, Orlando, FL.

McCafferty K Follman K Pasetti M, et al. . Covid vaccine responses during Sibeprenlimab treatment of IgA nephropathy (IgAN): an interim analysis. Nephrol Dial Transplant. 2023;38(S1):gfad063a_3347. doi:10.1093/ndt/gfad063a_3347 DOI

Barratt J Hour B Kooienga L, et al. . POS-109 Interim results of Phase 1 and 2 trials to investigate the safety, tolerability, pharmacokinetics, pharmacodynamics, and clinical activity of BION-1301 in patients with IgA nephropathy. Kidney Int Rep. 2022;7(2):S46. doi:10.1016/j.ekir.2022.01.121 DOI

Lafayette R Maes B Lin C, et al. . 36-Week efficacy & safety of atacicept 150 mg in the ORIGIN randomized, double-blind, placebo-controlled phase 2b study in IgAN and persistent proteinuria. ERA Congress. 2023. June 17, 2023.

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The role of BAFF and APRIL in IgA nephropathy: pathogenic mechanisms and targeted therapies

. 2023 ; 3 () : 1346769. [epub] 20240201

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