Pollution by chemicals and waste impacts human and ecosystem health on regional, national, and global scales, resulting, together with climate change and biodiversity loss, in a triple planetary crisis. Consequently, in 2022, countries agreed to establish an intergovernmental science-policy panel (SPP) on chemicals, waste, and pollution prevention, complementary to the existing intergovernmental science-policy bodies on climate change and biodiversity. To ensure the SPP's success, it is imperative to protect it from conflicts of interest (COI). Here, we (i) define and review the implications of COI, and its relevance for the management of chemicals, waste, and pollution; (ii) summarize established tactics to manufacture doubt in favor of vested interests, i.e., to counter scientific evidence and/or to promote misleading narratives favorable to financial interests; and (iii) illustrate these with selected examples. This analysis leads to a review of arguments for and against chemical industry representation in the SPP's work. We further (iv) rebut an assertion voiced by some that the chemical industry should be directly involved in the panel's work because it possesses data on chemicals essential for the panel's activities. Finally, (v) we present steps that should be taken to prevent the detrimental impacts of COI in the work of the SPP. In particular, we propose to include an independent auditor's role in the SPP to ensure that participation and processes follow clear COI rules. Among others, the auditor should evaluate the content of the assessments produced to ensure unbiased representation of information that underpins the SPP's activities.

Center for International Environmental Law Washington D C 20005 United States

Department of Applied Sciences Northumbria University Newcastle upon Tyne NE1 8ST United Kingdom

Department of Biological and Environmental Sciences University of Gothenburg 40530 Gothenburg Sweden

Department of Biology Norwegian University of Science and Technology 7491 Trondheim Norway

Department of Chemistry and Department of Mechanical Engineering Carnegie Mellon University Pittsburgh Pennsylvania 15217 United States

Department of Earth Sciences and School of the Environment University of Toronto Toronto M5S 3B1 Canada

Department of Environmental and Occupational Health Milken Institute School of Public Health The George Washington University Washington D C 20052 United States

Department of Environmental Chemistry IDAEA CSIC 08034 Barcelona Catalonia Spain

Department of Environmental Health Sciences School of Public Health and Health Sciences University of Massachusetts Amherst Amherst Massachusetts 01003 United States

Department of Environmental Science Stockholm University 10691 Stockholm Sweden

Department of Wildlife Fish and Environmental Studies Swedish University of Agricultural Sciences Umeå 907 36 Sweden

Department of Zoology Stockholm University Stockholm 114 18 Sweden

Division of Environmental Health Korea Environment Institute 30147 Sejong Republic of Korea

Eawag Swiss Federal Institute of Aquatic Science and Technology 8600 Dübendorf Switzerland

Environmental Technology Wageningen University and Research 6700 AA Wageningen The Netherlands

Food Packaging Forum Foundation 8045 Zurich Switzerland

Global Toxics and Human Rights Project American University Washington College of Law Washington D C 20016 United States

Graduate School of Oceanography University of Rhode Island Narragansett Rhode Island 02881 United States

Greenpeace Research Laboratories Department of Biosciences University of Exeter Exeter EX4 4RN United Kingdom

Indiana University Bloomington Indiana 47405 United States

Institute for Environmental Research RWTH Aachen University 52074 Aachen Germany

Institute for Environmental Sciences Landau RPTU Kaiserslautern Landau 76829 Landau Germany

Institute of Biogeochemistry and Pollutant Dynamics ETH Zürich 8092 Zürich Switzerland

Institute of Biophysics Carlos Chagas Filho Federal University of Rio de Janeiro 21941 902 Rio de Janeiro RJ Brazil

Institute of Marine Sciences University of Portsmouth Portsmouth PO4 9LY United Kingdom

International Panel on Chemical Pollution 8044 Zürich Switzerland

Key Laboratory of the Three Gorges Reservoir Region's Eco Environment Chongqing University 400045 Chongqing China

Marine Sciences University of Connecticut Groton Connecticut 06340 United States

National Institute for Environmental Studies 16 2 Onogawa Tsukuba 305 8506 Ibaraki Japan

RECETOX Masaryk University 625 00 Brno Czech Republic

School of Biological Sciences Monash University Melbourne 3800 Australia

School of Civil Engineering Universiti Sains Malaysia 14300 Nibong Tebal Penang Malaysia

State Key Laboratory of Pollution Control and Resource Reuse School of the Environment 210023 Nanjing China

State Key Laboratory of Soil and Sustainable Agriculture Institute of Soil Science Chinese Academy of Sciences Nanjing 210008 China

The Centre for Environmental and Climate Science Lund University 22362 Lund Sweden

University of British Columbia Vancouver BC V6T 1Z4 Canada

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