In light of recently published international guidelines concerning the diagnosis, treatment, and aftercare of urethral strictures and stenoses, the objective of this study was to synthesize an overview of guideline recommendations provided by the American Urological Association (AUA, 2023), the Société Internationale d'Urologie (SIU, 2010), and the European Association of Urology (EAU, 2023). The recommendations offered by these three associations, as well as the guidelines addressing urethral trauma from the EAU, AUA, and the Urological Society of India (USI), were assessed in terms of their guidance on posterior urethral stenosis. On the whole, the recommendations from the various guidelines exhibit considerable alignment. However, SIU and EAU place a stronger emphasis on the role of repeated endoscopic treatment compared to AUA. The preferred approach for managing radiation-induced bulbomembranous stenosis remains a subject of debate. Furthermore, endoscopic treatments enhanced with intralesional therapies may potentially serve as a significant treatment modality for addressing even fully obliterated stenoses.

Die vorliegende Arbeit verfolgte das Ziel, angesichts der kürzlich veröffentlichten internationalen Leitlinien zur Diagnose, Therapie und Nachsorge von Harnröhrenstrikturen und -stenosen eine Zusammenfassung der Empfehlungen der American Urological Association (AUA, 2023), der Société Internationale d’Urologie (SIU, 2010) und der European Association of Urology (EAU, 2023) zu erstellen. Die Empfehlungen dieser drei urologischen Gesellschaften sowie die Leitlinien zu Harnröhrentraumata der EAU, AUA und der Urological Society of India (USI) wurden hinsichtlich ihrer Therapiestrategien für posteriore Harnröhrenstenosen ausgewertet. Insgesamt zeigen sich weitgehende Übereinstimmungen in den Empfehlungen der verschiedenen Leitlinien. Im Vergleich zur AUA betonen SIU und EAU jedoch die Bedeutung wiederholter endoskopischer Behandlungen stärker. Die optimale Therapie für strahleninduzierte bulbomembranöse Stenosen bleibt ein kontrovers diskutiertes Thema. Zusätzlich könnten erweiterte endoskopische Behandlungen mit intraläsionalen Therapien eine wichtige Rolle bei der Behandlung von vollständig obliterierten Strikturen spielen.

Comprehensive Cancer Center Medizinische Universität Wien Universitätsklinik für Urologie Wien Österreich

Department of Urology 2nd Faculty of Medicine Charles University Prag Tschechien

Department of Urology University of Texas Southwestern Dallas TX USA

Department of Urology Weill Cornell Medical College New York NY USA

Hourani Center for Applied Scientific Research Al Ahliyya Amman University Amman Jordanien

Karl Landsteiner Institut für Urologie und Andrologie Wien Österreich

Klinik für Urologie Asklepios Klinik Barmbek Hamburg Deutschland

Klinik für Urologie Universitätsklinikum Frankfurt am Main Frankfurt am Main Deutschland

Klinik und Poliklinik für Urologie Universitätsklinikum Hamburg Eppendorf Martinistr 52 20246 Hamburg Deutschland

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