Paratesticular Dedifferentiated Liposarcoma with Rhabdomyoblastic Differentiation: A Case Report and Review of the Literature
Language English Country Czech Republic Media print
Document type Review, Case Reports, Journal Article
PubMed
38069650
DOI
10.14712/23362936.2023.35
PII: pmr_2023124040449
Knihovny.cz E-resources
- Keywords
- Dedifferentiated, Liposarcoma, Paratesticular, Rhabdomyoblasts,
- MeSH
- Humans MeSH
- Liposarcoma * diagnosis surgery pathology MeSH
- Genital Neoplasms, Male * surgery MeSH
- Orchiectomy MeSH
- Aged, 80 and over MeSH
- Testicular Neoplasms * diagnosis surgery MeSH
- Check Tag
- Humans MeSH
- Male MeSH
- Aged, 80 and over MeSH
- Publication type
- Journal Article MeSH
- Case Reports MeSH
- Review MeSH
Liposarcomas of the paratesticular tissue is a rare pathological entity. The symptoms are similar to inguinal hernias or hydroceles. We present the case of an 84-year-old man with a rare paratesticular liposarcoma that manifested as painless right hemiscrotal swelling. Testicular tumour markers were negative. Imaging revealed a heterogeneous mass with a fat component. He underwent a radical orchiectomy on the left side to remove the associated mass. This revealed dedifferentiated liposarcoma (DDLS) with rhabdomyoblastic differentiation and MDM2 amplification. The surgical margins were negative, and the patient had a metastatic workup that included magnetic resonance imaging (MRI) of the abdomen and pelvis. Because of the disease's rarity, there is no clear agreement on radiotherapy and chemotherapy roles.
Department of Pathology Istanbul Medeniyet University Istanbul Turkey
Department of Urology Hakkari Yuksekova State Hospital Hakkari Turkey
Department of Urology Istanbul Medeniyet University Istanbul Turkey
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