Consideration of hereditary effects in the radiological protection system: evolution and current status
Jazyk angličtina Země Velká Británie, Anglie Médium print-electronic
Typ dokumentu časopisecké články, přehledy
- Klíčová slova
- Ionizing radiation, doubling dose, hereditary effects, radiation genetic risk estimation, radiological protection,
- MeSH
- dávka záření MeSH
- hodnocení rizik MeSH
- lidé MeSH
- radiační expozice škodlivé účinky MeSH
- radiační ochrana * metody MeSH
- radiační poranění prevence a kontrola genetika MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
PURPOSE: The purpose of this paper is to provide an overview of the methodology used to estimate radiation genetic risks and quantify the risk of hereditary effects as outlined in the ICRP Publication 103. It aims to highlight the historical background and development of the doubling dose method for estimating radiation-related genetic risks and its continued use in radiological protection frameworks. RESULTS: This article emphasizes the complexity associated with quantifying the risk of hereditary effects caused by radiation exposure and highlights the need for further clarification and explanation of the calculation method. As scientific knowledge in radiation sciences and human genetics continues to advance in relation to a number of factors including stability of disease frequency, selection pressures, and epigenetic changes, the characterization and quantification of genetic effects still remains a major issue for the radiological protection system of the International Commission on Radiological Protection. CONCLUSION: Further research and advancements in this field are crucial for enhancing our understanding and addressing the complexities involved in assessing and managing the risks associated with hereditary effects of radiation.
Atomic Bomb Disease Institute Nagasaki University Nagasaki Japan
BfS Federal Office for Radiation Protection Oberschleißheim Germany
Centre for Occupational and Environmental Health The University of Manchester Manchester UK
CEPN Fontenay aux Roses France
Deptartment Radiation Oncology Technical University München Fontenay aux Roses France
Institute for Radiological Protection and Nuclear Safety Fontenay aux Roses France
Citace poskytuje Crossref.org